Weakly supervised bilayer convolutional network in segmentation of her2 related cells to guide her2 targeted therapies
CW Wang, KL Lin, H Muzakky, YJ Lin… - … Medical Imaging and …, 2023 - Elsevier
Overexpression of human epidermal growth factor receptor 2 (HER2/ERBB2) is identified as
a prognostic marker in metastatic breast cancer and a predictor to determine the effects of
ERBB2-targeted drugs. Accurate ERBB2 testing is essential in determining the optimal
treatment for metastatic breast cancer patients. Brightfield dual in situ hybridization (DISH)
was recently authorized by the United States Food and Drug Administration for the
assessment of ERRB2 overexpression, which however is a challenging task due to a variety …
a prognostic marker in metastatic breast cancer and a predictor to determine the effects of
ERBB2-targeted drugs. Accurate ERBB2 testing is essential in determining the optimal
treatment for metastatic breast cancer patients. Brightfield dual in situ hybridization (DISH)
was recently authorized by the United States Food and Drug Administration for the
assessment of ERRB2 overexpression, which however is a challenging task due to a variety …
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