… on the conformational free-energy characterizing B-to-A transition. From the investigation of
… changes in microenvironment around DNA are essential for regulating B-to-A DNA transition…

… that reoxygenation acts as a DNA-damaging event. … a picture of the tumor microenvironment
as an environment that is … Because these changes occur at the level of transcription, they …

… at the beginning of the transcription cycle to induce expression of pS2, … with transient local
changes in the microenvironment, as … as a DNA demethylase in the context of SAM deficiency. …

… vast changes at … Transcription of a DNA template with a hairpin formation produced RNA
that was approximately 10 nt longer or shorter than full-length due to slippage in transcription…

… of proteins that changed their chromatin association … transcription modulation, which likely
represent factors mediating epigenetic changes as well as those responding to the changes […

… transcription factors. Here, we show that inhibition of the BER pathway in an acidic tumor
microenvironment … For both the direct and indirect formation of SSBs, a DNA end processing …

… to changes in the microenvironment … vitro transcription reactions were conceived, as illustrated
in Figure 2. A series of promoter–template duplexes were assembled by annealing a DNA …

… in the hairpin–duplex conformational transition, the observed … As a control, we also
synthesized a DNA molecular-beacon-… In summary, microenvironment changes around the …

… a DNA sequence change, namely, the removal of a methyl group in the major groove of a
DNA … p labels are exploring a naturally occurring transition of the DNA backbone to establish (…

… Importantly, this protein is not only a DNA sensor but it is itself an ISG, and the activation of
… biological mechanisms linked to changes in the stem cell microenvironment and activation of …