… of long-term caffeine treatment on ligand binding to A 1 and A 2A receptors in the mouse
brain, … quantitative autoradiography, and on the amount of A 1 mRNA, as measured with in situ …

… So, in the present review we will focus on A1 and A2A adenosine receptors and on the
mechanisms they operate in order to infer how caffeine exerts most of its actions in the brain. …

… Caffeine is the most consumed psychoactive drug worldwide … targets of caffeine to modulate
activity in brain circuits are ill-… impact of caffeine using a concentration reached in the brain …

… of A1 and A2A receptors in the effects of caffeine on … Since the brain concentration of
caffeine is within 80% of its … expect that caffeine, beyond antagonizing adenosine A2A re…

… In fact, we observed that caffeine intake triggered an increased efficiency of A 1 R to control
synaptic transmission in the hippocampus but not in the prefrontal cortex or in the amygdala, …

… caffeine probably exerts its effects by blocking adenosine A1 … levels of adenosine A2A
receptors in the living brain using PET. … actions of caffeine and selective adenosine A2A receptor …

… Adenosine A1 and A2A receptors … A1 and A2A adenosine receptors, as well as the processes
by which they function, to deduce how caffeine exerts the majority of its effects in the brain (…

… brain targets mainly adenosine A1 and A2A receptors. The same as classical psychostimulants,
caffeine … or striatal administration of caffeine or an A1 but not an A2A receptor antagonist …

… of MAO inhibition by caffeine in the caffeine effect on MDMA-… A1 and A2A receptor blockade
may account for the caffeine-… sacrificed and their brains were histologically examined to …

… Adenosine receptor subtypes present in the brain include A1, A2A, A2B, and … caffeine-induced
AR antagonism in brain. A1AR and A2AAR are distributed differently throughout the brain. …