Cytotoxicity and genotoxicity of versicolorins and 5-methoxysterigmatocystin in A549 cells

D Jakšić, O Puel, C Canlet, N Kopjar, I Kosalec… - Archives of …, 2012 - Springer
… According to the results of the micronucleus test, VER A is a more potent genotoxic agent
than VER B, which correlates with their cytotoxic potential. Although the mechanism of …

Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

L Armand, A Tarantini, D Beal, M Biola-Clier… - …, 2016 - Taylor & Francis
… their genotoxic impact using long-term and low concentration exposure conditions. A549
alveolar epithelial cellsGenotoxic impact was assessed using alkaline and Fpg-modified comet …

Genotoxicity of hydroquinone in A549 cells

C Peng, D Arthur, F Liu, J Lee, Q Xia, MF Lavin… - Cell biology and …, 2013 - Springer
genotoxic effects of HQ in human lung cells. To this end, we evaluated the cytotoxicity
and genotoxicity of HQ in A549 cells, a human lung adenocarcinoma epithelial cell line. The …

Cytotoxicity, oxidative stress and genotoxicity induced by glass fibers on human alveolar epithelial cell line A549

V Rapisarda, C Loreto, C Ledda, G Musumeci… - Toxicology in vitro, 2015 - Elsevier
genotoxic effects and oxidative stress production induced by in vitro exposure of human
alveolar epithelial cells A549 … formazan produced by cells treated with an agent with the amount …

Genotoxic and inflammatory effects of organic extracts from traffic-related particulate matter in human lung epithelial A549 cells: the role of quinones

Y Shang, L Fan, J Feng, S Lv, M Wu, B Li, YS Zang - Toxicology in vitro, 2013 - Elsevier
genotoxic damages are less well known. In present study we aimed to examine the genotoxic
… PM (oTRP) in human lung epithelial A549 cells, and reveal the contributions from quinones…

Comparative genotoxicity of silver nanoparticles in human liver HepG2 and lung epithelial A549 cells

J Wang, B Che, LW Zhang, G Dong… - Journal of Applied …, 2017 - Wiley Online Library
… Therefore, in this study, the liver-derived HepG2 and lung epithelial A549 cell models were
applied to analyze the cytotoxicity and genotoxic response induced by AgNPs. A key DNA …

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

ML Jugan, S Barillet, A Simon-Deckers… - …, 2012 - Taylor & Francis
genotoxic potential to lung cells, and to link genotoxicity to physicochemical characteristics,
eg, size, specific surface area, crystalline phase. A549 cells … these NPs impair cell ability to …

Capsaicin-induced genotoxic stress does not promote apoptosis in A549 human lung and DU145 prostate cancer cells

A Lewinska, P Jarosz, J Czech, I Rzeszutek… - … /Genetic Toxicology and …, 2015 - Elsevier
… a DNA hypermethylating agent in A549 cells. In summary, we have shown that genotoxic
effects of capsaicin may contribute to limited susceptibility of DU145 and A549 cancer cells to …

Genotoxic effects of formaldehyde in the human lung cell line A549 and in primary human nasal epithelial cells

G Speit, O Schmid, S Neuss… - Environmental and …, 2008 - Wiley Online Library
… of crosslinking agents is the reduction of induced DNA migration, ie, after exposure to the
crosslinking agent, a defined DNA damage is induced by a DNA-strand breaking agent, and …

Response of PRIMPOL-Knockout Human Lung Adenocarcinoma A549 Cells to Genotoxic Stress

AS Gromova, EO Boldinova, DV Kim… - Biochemistry …, 2023 - Springer
… slowed down replication of nuclear and mitochondrial DNA under physiological conditions
and increased cell sensitivity to various genotoxic agents, such as UV radiation, methyl …