DNA damage response of A549 cells treated with particulate matter (PM10) of urban air pollutants
Y Sánchez-Pérez, YI Chirino, ÁR Osornio-Vargas… - Cancer letters, 2009 - Elsevier
… We describe the events triggered by a sub-lethal concentration of airborne particulate
matter (PM 10 ) in A549 cells, which include the formation DNA double-strand breaks, γH2A.X …
matter (PM 10 ) in A549 cells, which include the formation DNA double-strand breaks, γH2A.X …
Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549)
… Cell membrane lysis and mitochondrial ultrastructural disruption appeared to be the main …
2.5 on A549 cells. Concomitantly to the adverse effects observed in terms of cell mortality and …
2.5 on A549 cells. Concomitantly to the adverse effects observed in terms of cell mortality and …
Genotoxic potential of polycyclic aromatic hydrocarbons-coated onto airborne particulate matter (PM2. 5) in human lung epithelial A549 cells
S Billet, I Abbas, J Le Goff, A Verdin, V André… - Cancer Letters, 2008 - Elsevier
… cells were maintained at 37 C, in a humidified atmosphere containing 5% CO 2 . All the A549
cells … of DNA adduct pattern, on the other hand, derived from the same initial cell culture. …
cells … of DNA adduct pattern, on the other hand, derived from the same initial cell culture. …
Ambient particulate matter (PM2. 5): physicochemical characterization and metabolic activation of the organic fraction in human lung epithelial cells (A549)
S Billet, G Garçon, Z Dagher, A Verdin, F Ledoux… - Environmental …, 2007 - Elsevier
… To avoid phenotypic changes affecting responsiveness to chemicals, all the A549 cells we
used in the study of the cytotoxicity, on the one hand, and in the study of mRNA expression of …
used in the study of the cytotoxicity, on the one hand, and in the study of mRNA expression of …
[HTML][HTML] Particulate Matter (PM10) Promotes Cell Invasion through Epithelial–Mesenchymal Transition (EMT) by TGF-β Activation in A549 Lung Cells
CM García-Cuellar, M Santibáñez-Andrade… - International Journal of …, 2021 - mdpi.com
… From these, BEAS2B and A549 are the most frequently used … cell lines, we considered the
A549 cell line to be a more suitable model for the study of EMT, once that is a transformed cell …
A549 cell line to be a more suitable model for the study of EMT, once that is a transformed cell …
[HTML][HTML] The combined effects of physicochemical properties of size-fractionated ambient particulate matter on in vitro toxicity in human A549 lung epithelial cells
US Akhtar, N Rastogi, RD McWhinney, B Urch… - Toxicology Reports, 2014 - Elsevier
… effects associated with exposure to particulate matter (PM) are related … cellular responses
including: the induction of antioxidant defenses, proinflammatory responses, and ultimately cell …
including: the induction of antioxidant defenses, proinflammatory responses, and ultimately cell …
Oxidative damage induced in A549 cells by physically and chemically characterized air particulate matter (PM2.5) collected in Abidjan, Côte d'Ivoire
KS Kouassi, S Billet, G Garçon, A Verdin… - Journal of Applied …, 2010 - Wiley Online Library
… in cells, and the determination of extracellular lactate dehydrogenase (LDH) activity in cell-…
Thereafter, we looked for PM-induced oxidative damage in A549 cells through the production …
Thereafter, we looked for PM-induced oxidative damage in A549 cells through the production …
Water‐insoluble fraction of airborne particulate matter (PM10) induces oxidative stress in human lung epithelial A549 cells
S Yi, F Zhang, F Qu, W Ding - Environmental toxicology, 2014 - Wiley Online Library
… In this study, apoptotic cell death was examined after A549 cells were exposed to 10 μg/mL
of tPM 10 , iPM 10 , or PM 10 for 24h. As shown in Figure 5, all three preparations, …
of tPM 10 , iPM 10 , or PM 10 for 24h. As shown in Figure 5, all three preparations, …
Genotoxic and inflammatory effects of organic extracts from traffic-related particulate matter in human lung epithelial A549 cells: the role of quinones
Y Shang, L Fan, J Feng, S Lv, M Wu, B Li, YS Zang - Toxicology in vitro, 2013 - Elsevier
… up-regulated in A549 cells after treated with oTRP, as well as in A549 cells treated with NQ.
However, AQ exposure could not increase the levels of these two genes in A549 cells. The …
However, AQ exposure could not increase the levels of these two genes in A549 cells. The …
Properties and inflammatory effects of various size fractions of ambient particulate matter from Beijing on A549 and J774A. 1 cells
… Cytokines measured in this study included IL-8 for A549 cells and TNF-α for J774A.1 cells
and the results are shown in Figure 4. No significant difference between the control (C) and …
and the results are shown in Figure 4. No significant difference between the control (C) and …
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