Aberrant lipid metabolism as a therapeutic target in liver cancer

ED Pope III, EO Kimbrough, LP Vemireddy… - Expert opinion on …, 2019 - Taylor & Francis
Lipid metabolism has a role in HCC development; aberrant … Areas covered: We discuss
aberrant lipid metabolism and the … used: lipids, fatty acid metabolism, lipid metabolism, liver …

[HTML][HTML] Aberrant lipid metabolism: an emerging diagnostic and therapeutic target in ovarian cancer

CE Pyragius, M Fuller, C Ricciardelli… - International journal of …, 2013 - mdpi.com
… evidence that lipid metabolism is … lipid synthesis, which is regulated by metabolic and
oncogenic signalling pathways. This article reviews the latest knowledge on lipid metabolism and …

Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: a review

B Hu, JZ Lin, XB Yang, XT Sang - Cell proliferation, 2020 - Wiley Online Library
… of fatty acid (FA) where the aberrantly activated oncogenic signalling pathways alter the
lipid-… way for therapeutically targeting the aberrant lipid metabolism to benefit the HCC patients. …

Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling

AD Patterson, O Maurhofer, D Beyoğlu, C Lanz… - Cancer research, 2011 - AACR
There has been limited analysis of the effects of hepatocellular carcinoma (HCC) on liver
metabolism and circulating endogenous metabolites. Here, we report the findings of a plasma …

Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells

M Visweswaran, F Arfuso, S Warrier… - Stem cells, 2020 - academic.oup.com
aberrant lipid metabolism that CSCs exploit to boost their survival, which comprises upregulation
in de novo lipogenesis, lipid droplet synthesis, lipid … in CSCs' lipid metabolism, which …

Aberrant lipid metabolism in cancer cells–the role of oncolipid‐activated signaling

U Ray, SS Roy - The FEBS journal, 2018 - Wiley Online Library
lipid synthesis through up-regulation of sterol regulatory element-binding protein 1, a master
regulator of lipid metabolism. … signaling in regard to lipid metabolism in cancers. Future work …

[HTML][HTML] Evidence of aberrant lipid metabolism in hepatitis C and hepatocellular carcinoma

JM Wu, NJ Skill, MA Maluccio - HPB, 2010 - Elsevier
… This study aimed to explore lipid metabolism in hepatitis C virus (HCV) and HCV-… of lipid
metabolism in HCV cirrhotic patients and HCV cirrhotic cancer patients. To this end, serum lipids

[HTML][HTML] Aberrant lipid metabolism in hepatocellular carcinoma revealed by liver lipidomics

Z Li, M Guan, Y Lin, X Cui, Y Zhang, Z Zhao… - International journal of …, 2017 - mdpi.com
… Background: The aim of this study was to characterize the disorder of lipid metabolism in …
the disorder of lipid metabolism in HCC is very limited. Study of lipid metabolism in liver cancer …

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

S Fu, L Yang, P Li, O Hofmann, L Dicker, W Hide, X Lin… - Nature, 2011 - nature.com
… We carried out two different but complementary approaches to correct aberrant lipid metabolism
induced SERCA dysfunction and examined the effects on ER homeostasis in the obese …

[HTML][HTML] Intestinal failure and aberrant lipid metabolism in patients with DGAT1 deficiency

JM van Rijn, RC Ardy, Z Kuloğlu, B Härter… - Gastroenterology, 2018 - Elsevier
… have produced cell models that recapitulate an altered lipid metabolism in vitro. Here, we
show … We have demonstrated aberrant lipid metabolism as evidenced by reduced lipid droplet …