[HTML][HTML] Abiraterone acetate in the treatment of prostate cancer

A Thakur, A Roy, A Ghosh, M Chhabra… - Biomedicine & …, 2018 - Elsevier
… of patients suffering from prostate cancer. In this prevailing scenario, abiraterone acetate (AA)
has proved to be a boon for patients suffering from prostate cancer. AA selectively inhibits …

[HTML][HTML] Abiraterone and increased survival in metastatic prostate cancer

JS De Bono, CJ Logothetis, A Molina… - … England Journal of …, 2011 - Mass Medical Soc
… progressing castration-resistant prostate cancer who had not received … abiraterone acetate
and prednisone would improve overall survival among patients with advanced prostate cancer

Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind …

K Fizazi, HI Scher, A Molina, CJ Logothetis… - The lancet …, 2012 - thelancet.com
… This final analysis confirms that abiraterone acetate significantly prolongs overall survival
in patients with metastatic castration-resistant prostate cancer who have progressed after …

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer

G Attard, AHM Reid, R A'Hern, C Parker… - Journal of clinical …, 2009 - ascopubs.org
… , and irreversible inhibitor of CYP17, abiraterone, 13,14 which … the antitumor activity of
abiraterone acetate, this phase I … the antitumor activity of abiraterone acetate administered at 1,000 …

Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two …

G Attard, L Murphy, NW Clarke, W Cross, RJ Jones… - The lancet, 2022 - thelancet.com
… There was no evidence of a difference in metatasis-free survival when enzalutamide and
abiraterone acetate were administered concurrently compared with abiraterone acetate alone (…

The role of abiraterone acetate in the management of prostate cancer: a critical analysis of the literature

G Sonpavde, G Attard, J Bellmunt, MD Mason… - European urology, 2011 - Elsevier
… Hence, the term castration-resistant prostate cancer (CRPC) is … analyse the emerging role of
abiraterone acetate (AA), a … The key enzyme inhibited by abiraterone acetate (AA) is CYP17, …

Abiraterone acetate plus prednisone versus prednisone alone in chemotherapy-naive men with metastatic castration-resistant prostate cancer: patient-reported …

E Basch, K Autio, CJ Ryan, P Mulders, N Shore… - The lancet …, 2013 - thelancet.com
Abiraterone acetate plus prednisone significantly improves radiographic progression-free …
patients with metastatic castration-resistant prostate cancer compared with prednisone alone. …

[HTML][HTML] Abiraterone in metastatic prostate cancer without previous chemotherapy

CJ Ryan, MR Smith, JS De Bono… - … England Journal of …, 2013 - Mass Medical Soc
… In this double-blind study, we randomly assigned 1088 patients to receive abiraterone acetate
(1000 mg) plus prednisone (5 mg twice daily) or placebo plus prednisone. The coprimary …

Abiraterone acetate: a review of its use in patients with metastatic castration-resistant prostate cancer

SM Hoy - Drugs, 2013 - Springer
Abiraterone acetate is approved … prostate cancer (CRPC). When administered in combination
with prednisone in a placebo-controlled, multinational phase III study, abiraterone acetate

[HTML][HTML] Abiraterone for prostate cancer not previously treated with hormone therapy

ND James, JS de Bono, MR Spears… - … England Journal of …, 2017 - Mass Medical Soc
Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate
cancer. We assessed the effect of this combination in men starting long-term androgen-…