Understanding and overcoming the mechanisms of primary and acquired resistance to abiraterone and enzalutamide in castration resistant prostate cancer

C Buttigliero, M Tucci, V Bertaglia, F Vignani… - Cancer treatment …, 2015 - Elsevier
… survival, including enzalutamide and abiraterone, two new-… with abiraterone and 25% of
those treated with enzalutamide … of resistance to abiraterone and enzalutamide, and to discuss …

Comparing sequencing of abiraterone and enzalutamide in men with metastatic castration‐resistant prostate cancer: a retrospective study

BL Maughan, B Luber, R Nadal, ES Antonarakis - The Prostate, 2017 - Wiley Online Library
… system for treatment with abiraterone and enzalutamide. Only patients that received
sequential therapy with abiraterone-to-enzalutamide or enzalutamide-to-abiraterone (without any …

[HTML][HTML] Cabazitaxel versus abiraterone or enzalutamide in metastatic prostate cancer

R de Wit, J de Bono, CN Sternberg… - … England Journal of …, 2019 - Mass Medical Soc
abiraterone or enzalutamide in patients with metastatic castration-resistant prostate cancer
… androgen-signaling–targeted inhibitor (abiraterone or enzalutamide). The trial was approved …

Efficacy of abiraterone and enzalutamide in pre‐and postdocetaxel castration‐resistant prostate cancer: a trial‐level meta‐analysis

M Fang, M Nakazawa, ES Antonarakis, C Li - Prostate Cancer, 2017 - Wiley Online Library
… in pre- and postdocetaxel settings in castration-resistant prostate cancer (CRPC) … of abiraterone
and enzalutamide with respect to OS and PFS. In the predocetaxel setting, enzalutamide

Comparing the clinical efficacy and safety of abiraterone and enzalutamide in metastatic castration-resistant prostate cancer: A systematic review and meta-analysis

X Wang, H Yang, X Hu, W Wang, X Yu… - Journal of Oncology …, 2021 - journals.sagepub.com
… Our results demonstrated that enzalutamide was more efficacious than abiraterone for
patients with metastatic castration-resistant prostate cancer, but was associated with a …

Abiraterone alone or in combination with enzalutamide in metastatic castration-resistant prostate cancer with rising prostate-specific antigen during enzalutamide …

G Attard, M Borre, H Gurney, Y Loriot… - Journal of Clinical …, 2018 - ascopubs.org
… Combining abiraterone with enzalutamide would not inhibit reactivation of AR independent
… for cancers more likely to benefit from the combination of enzalutamide and abiraterone, we …

Abiraterone or Enzalutamide in Advanced Castration‐Resistant Prostate Cancer: An Indirect Comparison

A Chopra, M Georgieva, G Lopes, CM Yeo… - … Prostate, 2017 - Wiley Online Library
… of abiraterone acetate and enzalutamide in advanced CRPC. Our results show that in a
pre-docetaxel setting, enzalutamide … that enzalutamide may outperform AA with abiraterone in …

… versus enzalutamide in patients with metastatic castration-resistant prostate cancer: a systematic review and meta-analysis: Abiraterone versus enzalutamide in …

X Wang, S Wang, X Hu, X Yu… - … of Pharmacy & …, 2020 - journals.library.ualberta.ca
… ABSTRACT- Purpose: To compare the effectiveness and safety between abiraterone and
enzalutamide in the treatment of patients with metastatic castration-resistant prostate cancer (…

[HTML][HTML] Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two …

G Attard, L Murphy, NW Clarke, W Cross, RJ Jones… - The lancet, 2022 - thelancet.com
… and the second trial, which included enzalutamide, allocated 533 to the control group …
enzalutamide and abiraterone acetate were administered concurrently compared with abiraterone

Enzalutamide (ENZA) in combination with abiraterone acetate (AA) in bone metastatic castration resistant prostate cancer (mCRPC).

E Efstathiou, MA Titus, S Wen, A SanMiguel, A Hoang… - 2014 - ascopubs.org
5000 Background: Co-targeting the androgen receptor (AR) and paracrine androgen biosynthesis
in mCRPC may be more effective than either alone. This study aims to evaluate safety…