Abscopal, immunological effects of radiotherapy: narrowing the gap between clinical and preclinical experiences
N Brix, A Tiefenthaller, H Anders, C Belka… - Immunological …, 2017 - Wiley Online Library
… We will briefly outline the history of RT-induced abscopal effects as well as the RT-mediated …
However, with the development of novel immunotherapeutic agents, including checkpoint …
However, with the development of novel immunotherapeutic agents, including checkpoint …
Nanotechnology‐enhanced radiotherapy and the abscopal effect: Current status and challenges of nanomaterial‐based radio‐immunotherapy
… abscopal effects. Radiation therapy treatment parameters are also important variables to
control to maximize the abscopal effect, as they have a large effect … had a significant impact on …
control to maximize the abscopal effect, as they have a large effect … had a significant impact on …
The abscopal effect of radiation therapy
DJ Craig, NS Nanavaty, M Devanaboyina… - Future …, 2021 - Taylor & Francis
… To maximize abscopal effect outcomes of RT and immunotherapy, predictive biomarkers
can be combined with post-treatment indicators. Further studies should evaluate mechanisms …
can be combined with post-treatment indicators. Further studies should evaluate mechanisms …
[HTML][HTML] Abscopal effect of stereotactic radiotherapy combined with anti‐PD‐1/PD‐L1 immunotherapy: Mechanisms, clinical efficacy, and issues
H Zhuang - Cancer Communications, 2020 - ncbi.nlm.nih.gov
… and SABR were used sequentially or at the same time. If the … abscopal effect, as it is probably
induced by immunotherapy … immunotherapy but obtain relief in local as well as abscopal …
induced by immunotherapy … immunotherapy but obtain relief in local as well as abscopal …
The immune mechanisms of abscopal effect in radiation therapy
… abscopal effect from RT alone is rare and protracted. Nevertheless, modern hypofractionated
RT in combination with more effective immunotherapy is heralding an era … immunotherapy …
RT in combination with more effective immunotherapy is heralding an era … immunotherapy …
Strategies to improve cancer immune checkpoint inhibitors efficacy, other than abscopal effect: A systematic review
… of immunotherapy … to immunotherapy but it also acts in a synergistic manner in two significant
ways: (a) Induction of immunogenic cell death as part of its independent therapeutic effects …
ways: (a) Induction of immunogenic cell death as part of its independent therapeutic effects …
The controversial abscopal effect
JM Kaminski, E Shinohara, JB Summers… - Cancer treatment …, 2005 - Elsevier
… body of knowledge about the abscopal effect and attempt to answer … abscopal effect
apparently operates through mechanisms that are paralleled in gene therapy, local immunotherapy…
apparently operates through mechanisms that are paralleled in gene therapy, local immunotherapy…
The systemic immunostimulatory effects of radiation therapy producing overall tumor control through the abscopal effect
MA D'Andrea, GK Reddy - Journal of Radiation Oncology, 2019 - Springer
… abscopal effects in a wide variety of malignant tumors. With the advent of novel immunotherapies,
… A clinical consideration of the abscopal effects produced by radiation therapy could …
… A clinical consideration of the abscopal effects produced by radiation therapy could …
[HTML][HTML] Abscopal effect following radiation therapy in cancer patients: a new look from the immunological point of view
J Welsh, JJ Bevelacqua, L Dobrzyński… - Journal of Biomedical …, 2020 - ncbi.nlm.nih.gov
… The abscopal effect was practically unheard of just ten years ago. Today, you cannot go to
a … dealing with the abscopal effect and the integration of modern immunotherapy using high-…
a … dealing with the abscopal effect and the integration of modern immunotherapy using high-…
[HTML][HTML] Harnessing the abscopal effect for gastrointestinal malignancies in the era of immunotherapy
C Hino, EW Lee, GY Yang - Journal of Gastrointestinal Oncology, 2023 - ncbi.nlm.nih.gov
… radiation therapy (RT) with immunotherapy may work synergistically to improve … of the
abscopal effect. In this review, we discuss the rationale for RT in combination with immunotherapy. …
abscopal effect. In this review, we discuss the rationale for RT in combination with immunotherapy. …