[HTML][HTML] Abscopal Effect on Bone Metastases from Solid Tumors: A Systematic Review and Retrospective Analysis of Challenge within a Challenge

M Tomaciello, M Conte, FR Montinaro, A Sabatini… - Biomedicines, 2023 - mdpi.com
… studies; 82 dealt with an abscopal effect, not on BMs; in 6 articles the AE was a consequence
of chemotherapy–immunotherapy treatments without the involvement of radiotherapy; and …

[HTML][HTML] The abscopal effect: a sense of DNA damage is in the air

TP Lippert, RA Greenberg - The Journal of Clinical …, 2021 - Am Soc Clin Investig
… This away-from-target or “abscopal effect” received fringe attention because of its rarity. With
the advent of immunotherapy, there are now increasing reports of abscopal effects upon RT …

A possible abscopal effect of post-irradiation immunotherapy in two patients with metastatic lung tumors

K Kodama, M Higashiyama, J Okami… - International Cancer …, 2014 - Springer
… metastases and then innate immunotherapy using the cell wall … and 2 months after the
immunotherapy, all lung metastases … of RT and immunotherapy will elicit abscopal effects that can …

[HTML][HTML] Tumor microenvironment shows an immunological abscopal effect in patients with NSCLC treated with pembrolizumab-radiotherapy combination

LL van der Woude, MAJ Gorris, IMN Wortel… - … for ImmunoTherapy …, 2022 - ncbi.nlm.nih.gov
… an immunological abscopal effect of the SBRT and anti-PD-1 therapy combination. The
abscopal effect of radiotherapy alone is rare. It is believed that most of the time, tumors employ …

[HTML][HTML] Abscopal effects of local radiotherapy are dependent on tumor immunogenicity

JZ Lai, YY Zhu, Y Liu, LL Zhou, L Hu, L Chen… - Frontiers in …, 2021 - frontiersin.org
… predict the abscopal effect of … in abscopal effects and highlights the impact of tumor
heterogeneity on the therapeutic efficacy of radiotherapy and their combination with immunotherapy

[HTML][HTML] Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?

I Jatoi, JR Benson, I Kunkler - NPJ Breast Cancer, 2018 - nature.com
immunotherapy trials demonstrating treatment efficacy. In this article, we hypothesize that
an abscopal effect may … this effect with systemic agents to reduce the risk of late recurrences. …

Overview of the synergistic use of radiotherapy and immunotherapy in cancer treatment: current challenges and scopes of improvement

RR Colciago, I Fischetti, C Giandini… - Expert Review of …, 2023 - Taylor & Francis
… combined therapy, individuals who would benefit the most from this treatment, how to achieve
abscopal effect and when does radio-immunotherapy become standard clinical practice. …

Extracranial abscopal effect induced by combining immunotherapy with brain radiotherapy in a patient with lung adenocarcinoma: A case report and literature review

X Lin, T Lu, Z Xie, Y Qin, M Liu, X Xie, S Li… - Thoracic …, 2019 - Wiley Online Library
immunotherapy before radiotherapy. Our case indicates that abscopal effects can be induced
… at tumor sites with low immunogenicity if radiotherapy is combined with immunotherapy. …

[HTML][HTML] Abscopal effect of radiotherapy enhanced with immune checkpoint inhibitors of triple negative breast cancer in 4T1 mammary carcinoma model

HN Song, H Jin, JH Kim, IB Ha, KM Kang… - International Journal of …, 2021 - mdpi.com
… and immunotherapy may even lead to an improved systemic effect, also known as the “abscopal
effect… In this study, we aimed to demonstrate the abscopal effect in a preclinical model of …

Pivotal roles of tumor‐draining lymph nodes in the abscopal effects from combined immunotherapy and radiotherapy

Z Liu, Z Yu, D Chen, V Verma, C Yuan… - Cancer …, 2022 - Wiley Online Library
… -induced anti-tumor and abscopal effects in a murine model … We next interrogated whether
iRT-stimulated abscopal effects … -1 antibody induced dominant abscopal effects in the bilateral …