… Almost two-thirds of these survivors are age 65 or older. Given this, it is … of cancer and its
therapies on the aging process. Childhood cancer survivors, diagnosed with cancer at age 21 or …

… Advances in treatment for childhood cancer have resulted in more than 360,000 childhood
cancer … Treatment for childhood cancer is multimodal, and includes surgery, radiation, and …

… The mechanisms of accelerated aging in cancer survivors … shown that cancer treatment
leads to accelerated aging, which … diseases in CCSs and in adult cancer survivors (16). …

… Although this study provides novel information and intriguing insights into understanding
the accelerated aging among childhood cancer survivors, our findings should be interpreted in …

… murine models lead to both cancer and the tissue degeneration normally seen in old age,
120,121 … risk of both cancer and accelerated aging among childhood cancer survivors whose …

… as a mediator of early aging and frailty among cancer survivors (molecular changes [… age,
we measured PBTL p16 mRNA levels among young adult survivors of childhood cancers and …

… We report that childhood cancer survivors demonstrate a pro-inflammatory status characterized
by increase in inflammatory markers: C-reactive protein and fibrinogen, as well as a shift …

… Background: Survivors of childhood cancer have functional limitations and health-related
morbidity consistent with an accelerated aging phenotype. We characterized aging using a …

… of accelerated aging. Most of the existing evidence for an accelerated aging state in cancer
… Numerous studies have shown that survivors of childhood cancers are more predisposed to …

… inflamm-aging key biomarkers in childhood cancer survivors could … , used to counteract
inflamm-aging, may prevent side effects. … mitochondrial infidelity and accelerated aging in CCS. …