… Voltage-gated sodium channels are integral membrane proteins that initiate and propagate
the electrical action potential in excitable cells, by selectively allowing influx of sodium ions …

… many of the reconstituted sodium channels contribute to our ion-flux measurements. First, the
… of vesicles whose internal volume is accessible to veratridine-activated sodium channels. If …

… , which regulates the passage of not only MTSET but also sodium ions through the channel
… act as surrogates for sodium ions. MTSET is much larger than these four ions, so it certainly …

… a sodium channel S4 segment was examined by cysteine scanning mutagenesis and testing
accessibility … way that many ion channels achieve highly selective and rapid ion permeation …

… sodium storage is further proved. As a consequence, constructing hard carbons with abundant
closed pores as well as accessible channels is necessary for high performance anodes. …

… of voltage-dependent gating, ion selectivity and drug block in Na V and Ca V channels. …
–function studies of Na V channels: a large external vestibule accessible to hydrophilic reagents; …

… As a control, we simulated the Na + permeation in a prokaryotic Na V channel, Na V Rh,
and produced the ion density map following the same protocol. Notably, Na V Rh presents a …

… the conductance process in sodium channels. These studies simulate sodium channel
conductance based on an experimentally determined structure of a sodium channel pore that has …

… Structural fluctuations of these ionic clusters result in many accessible ion-binding modes
and foster a highly degenerate, liquid-like energy landscape that promotes Na + diffusion. By …

… epithelial sodium channel (ENaC)/degenerin (DEG) gene family encodes sodium channels
… in snails is a ligand-gated channel activated by neuropeptides, and theDrosophila subfamily …