… of ACE2 in modulating the innate immune system and tissue repair cascades and anchors its
therapeutic … the current efforts of exploiting ACE2 as a therapeutic target to address this dire …

… review the current therapeutic and vaccine developments related to blocking ACE2 and S
protein interactions and inhibiting RAS, anti-SARS-CoV-2 drugs, and immune-based therapy. …

… implications. Potential therapies aimed at intercepting SARS-CoV-2 from reaching the full-length
membrane-bound ACE2 receptor using soluble ACE2 protein and other potential …

… proposes that ACE2 targeted strategy could be employed as a potential therapeutic intervention
for … Thus, the present article is aimed to discuss the ACE-2 receptors and their role in the …

… enzyme with its physiological and pathophysiological implications; (iii… ACE2 drug design;
(vi) the current status of genetic targeting of the RAS; (vii) the potential of ACE2 as a therapeutic …

… ACE-2 expression, which could favour SARS-CoV-2 infection of host’s cells and tissues. By
contrast, in patients treated with ACE-Is and ARBs, ACE-2 … to increase ACE-2 expression in …

… ACE2 receptors on cell surfaces to gain intracellular entry, making them an ideal target for
therapy. High-… forms of the ACE2 protein as a decoy receptor to neutralize COVID-19 infection. …

… There are many possible targets in addition to ACE2, thus combined therapies may be …
some of these therapeutic strategies, which have a special focus on adjuvant therapies to prevent …

… This single-stranded RNA virus uses Angiotensin-converting enzyme 2 (ACE2) as a receptor
for entry into the host cell. Overexpression of ACE2 is mainly observed in hypertensive, …

… ACE2 in relation to pulmonary hypertension and provide proof of principle for its therapeutic
… This review focuses on the role of ACE2 in the pathobiology of pulmonary hypertension and …