Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
Z Sun, YE Chin, DD Zhang - Molecular and cellular biology, 2009 - Am Soc Microbiol
… p300/CBP directly acetylates Nrf2 in response to arsenite-induced stress. We have identified
multiple acetylated lysine residues within the Nrf2 … acetylation sites, with no effects on Nrf2 …
multiple acetylated lysine residues within the Nrf2 … acetylation sites, with no effects on Nrf2 …
[HTML][HTML] The acetyltransferase p300 regulates NRF2 stability and localization
A Ganner, ZC Pfeiffer, L Wingendorf, S Kreis… - Biochemical and …, 2020 - Elsevier
… Acetylation of NRF2 by p300/CBP augments its DNA binding … modification of NRF2 by
p300/CBP the molecular … p300 and NRF2 has been shown to be acetylated by p300 [5…
p300/CBP the molecular … p300 and NRF2 has been shown to be acetylated by p300 [5…
[HTML][HTML] Inhibition of p300/CBP-associated factor attenuates renal tubulointerstitial fibrosis through modulation of NF-kB and Nrf2
S Chung, S Kim, M Son, M Kim, ES Koh… - International journal of …, 2019 - mdpi.com
… , Sas2, and Tip60) family, p300/CBP family, and nuclear coactivators (NRC) … acetylation of
lysine residues on histones H2B, H3, and H4 [1]. As a member of the GNAT family, p300/CBP-…
lysine residues on histones H2B, H3, and H4 [1]. As a member of the GNAT family, p300/CBP-…
[HTML][HTML] CBP-1/p300 acetyltransferase regulates SKN-1/Nrf cellular levels, nuclear localization, and activity in C. elegans
A Ganner, J Gerber, AK Ziegler, Y Li, J Kandzia… - Experimental …, 2019 - Elsevier
… indicate that CBP/p300 binds Nrf2, induces its acetylation, and facilitates binding of Nrf2 to
its … Although interaction of CBP/p300 with Nrf2 and its acetylation have been described the …
its … Although interaction of CBP/p300 with Nrf2 and its acetylation have been described the …
[HTML][HTML] NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
… (CBP) from Nrf2 by competitive interaction with the CH1-KIX domain of CBP, which results in
inactivation of Nrf2. … (E) Effect of the HDAC1 and 3 on the CBP-mediated MafK acetylation in …
inactivation of Nrf2. … (E) Effect of the HDAC1 and 3 on the CBP-mediated MafK acetylation in …
[HTML][HTML] Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic …
Y Kawai, LK Garduno, M Theodore, J Yang… - Journal of Biological …, 2011 - ASBMB
… acetylation of Nrf2, increased binding of Nrf2 to its cognate response element in a target
gene promoter, and increased Nrf2-… ) decreased acetylation of Nrf2 as well as Nrf2-dependent …
gene promoter, and increased Nrf2-… ) decreased acetylation of Nrf2 as well as Nrf2-dependent …
Mechanistic Study of Nucleocytoplasmic Trafficking and Reversible Acetylation in Modulating the NRF2-Dependent Antioxidant Response
Z Sun - 2008 - repository.arizona.edu
… of Nrf2 mediated by transcription co-activator p300/CBP. We show that p300/CBP directly
binds and acetylates Nrf2 … We have identified multiple acetylated lysine residues within the Nrf2 …
binds and acetylates Nrf2 … We have identified multiple acetylated lysine residues within the Nrf2 …
[HTML][HTML] Downregulation of P300/CBP-associated factor protects from vascular aging via Nrf2 signal pathway activation
L Qiu, X Liu, H Xia, C Xu - International Journal of Molecular Sciences, 2022 - mdpi.com
… P300/CBP-associated factor (PCAF), also known as lysine … acetylation transfer enzyme
family, PCAF is mainly involved in the transcriptional regulation of genes through acetylation of …
family, PCAF is mainly involved in the transcriptional regulation of genes through acetylation of …
[HTML][HTML] Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation
L Yang, X Chen, Z Bi, J Liao, W Zhao… - The Korean Journal …, 2021 - synapse.koreamed.org
… of p300/CBP and histone acetylation in renal … p300/CBP mediated regulation of caspase-3/-9
in IRI rats. Our data reveal that the inhibition of JNK/p300/CBP mediated histone acetylation …
in IRI rats. Our data reveal that the inhibition of JNK/p300/CBP mediated histone acetylation …
The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression
W Wang, K Pan, Y Chen, C Huang… - Nucleic acids …, 2012 - academic.oup.com
… p300/CBP and is acetylated by p300/CBP. The function of TSA is to inhibit the HDAC activity
and allow the p300/CBP-dependent acetylation … INK4A when p300/CBP are knocked-down. …
and allow the p300/CBP-dependent acetylation … INK4A when p300/CBP are knocked-down. …