[HTML][HTML] Selective coactivation of α7-and α4β2-nicotinic acetylcholine receptors reverses beta-amyloid–induced synaptic dysfunction
JP Roberts, SA Stokoe, MF Sathler, RA Nichols… - Journal of Biological …, 2021 - ASBMB
… Aβ can alter neuronal signaling through interactions with nicotinic acetylcholine receptors
(nAChRs), contributing to synaptic dysfunction in AD. The three major nAChR subtypes in the …
(nAChRs), contributing to synaptic dysfunction in AD. The three major nAChR subtypes in the …
Co-activation of selective nicotinic acetylcholine receptors is required to reverse beta amyloid–induced Ca2+ hyperexcitation
JL Sun, SA Stokoe, JP Roberts, MF Sathler, KA Nip… - Neurobiology of …, 2019 - Elsevier
… A potential target of Aβ42 is the nicotinic acetylcholine receptor (nAChR). … We suggest
co-activation of α7 and α4β2 nAChRs is … We further reveal co-activation of α7 and α4β2 nAChRs is …
co-activation of α7 and α4β2 nAChRs is … We further reveal co-activation of α7 and α4β2 nAChRs is …
The effect of coactivation of muscarinic and nicotinic acetylcholine receptors on LTD in the hippocampal CA1 network
E Sugisaki, Y Fukushima, S Fujii, Y Yamazaki, T Aihara - Brain Research, 2016 - Elsevier
… , and ACh activates muscarinic (mAChR) and nicotinic (nAChR) acetylcholine receptors. …
The neuromodulator ACh activates both muscarinic acetylcholine receptors (mAChRs) and …
The neuromodulator ACh activates both muscarinic acetylcholine receptors (mAChRs) and …
Coactivation of resistance vessels and muscle fibers with acetylcholine release from motor nerves
… ings indicate that ACh “spillover” from NMJs can coactivate … receptors, giving rise to a dilation
that is conducted into feed … In the present study, we tested the hypothesis that ACh released …
that is conducted into feed … In the present study, we tested the hypothesis that ACh released …
Coactivation of β-adrenergic and cholinergic receptors enhances the induction of long-term potentiation and synergistically activates mitogen-activated protein kinase …
AM Watabe, PA Zaki, TJ O'Dell - Journal of Neuroscience, 2000 - Soc Neuroscience
… of β-adrenergic and cholinergic receptor agonists on cAMP levels… that coactivation of β-adrenergic
and cholinergic receptors … that coactivation of noradrenergic and cholinergic receptors …
and cholinergic receptors … that coactivation of noradrenergic and cholinergic receptors …
Muscle coactivation: definitions, mechanisms, and functions
ML Latash - Journal of neurophysiology, 2018 - journals.physiology.org
… coactivation … coactivation within an agonist-antagonist pair is reduction in the resultant forces
and moments as compared with those that could be expected in the absence of coactivation…
and moments as compared with those that could be expected in the absence of coactivation…
Input-selective potentiation and rebalancing of primary sensory cortex afferents by endogenous acetylcholine
MC Kuo, DD Rasmusson, HC Dringenberg - Neuroscience, 2009 - Elsevier
… The role of different classes of cholinergic receptors (muscarinic, nicotinic) was assessed
by pharmacological manipulations. Also, a potential involvement of N-methyl-d-aspartate (…
by pharmacological manipulations. Also, a potential involvement of N-methyl-d-aspartate (…
Muscarinic acetylcholine receptors act in synergy to facilitate learning and memory
… supports learning but is detrimental to memory retrieval, we found that coactivation of multiple
mAChR is required for retrieval of both recently and remotely acquired context memories. …
mAChR is required for retrieval of both recently and remotely acquired context memories. …
Selective Co‐activation of α7 and α4β2 Nicotinic Acetylcholine Receptors Reverses Beta‐amyloid‐induced Synaptic Dysfunction Jessica P. Roberts1,2,4, Sarah A. Stokoe1,2,4, Matheus F. Sathler2, Robert A. Nichols3, Seonil …
J Roberts - The FASEB Journal, 2021 - Wiley Online Library
… Aβ can alter neuronal signaling through interactions with nicotinic acetylcholine receptors
(nAChRs), contributing to synaptic dysfunction in AD. The three major nAChR subtypes in the …
(nAChRs), contributing to synaptic dysfunction in AD. The three major nAChR subtypes in the …
Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement
… This nicotine addiction is mediated through the nicotinic acetylcholine receptor (nAChR),
expressed on most neurons, and also many other organs in the body. Even within the ventral …
expressed on most neurons, and also many other organs in the body. Even within the ventral …