The Effect of Colistin Resistance-Associated Mutations on the Fitness of Acinetobacter baumannii

X Mu, N Wang, X Li, K Shi, Z Zhou, Y Yu… - Frontiers in …, 2016 - frontiersin.org
… had an altered antibiotic resistance profile. The compensatory mutations partially or completely
rescued the LPS-deficient’s fitness, suggesting that compensatory mutations … baumannii. …

[PDF][PDF] Genomic fitness profiling of Acinetobacter baumannii reveals modes of action for common biocides and mechanisms of biocide-antibiotic antagonism

…, F Short, K Hassan, V Naidu, A Pokhrel… - Research …, 2021 - pdfs.semanticscholar.org
… resistant nosocomial pathogen Acinetobacter baumannii, that … baumannii tness on biocides,
we proposed and con rmed that … baumannii tolerance to antibiotics that have intracellular …

Interplay between Colistin Resistance, Virulence and Fitness in Acinetobacter baumannii

GJ Da Silva, S Domingues - Antibiotics, 2017 - mdpi.com
Acinetobacter baumannii is an important opportunistic … baumannii strains. Colistin is a cationic
peptide that disrupts the … is often associated with a reduced bacterial fitness. Therefore, the …

In vitro and in vivo fitness of clinical isolates of carbapenem-resistant and-susceptible Acinetobacter baumannii

S Kumar, L Singhal, P Ray, V Gautam - Indian journal of medical …, 2020 - Elsevier
… Context: Acinetobacter baumannii is one among the leading nosocomial pathogens in
the … Limited data on relative fitness and virulence of carbapenem-resistant A. baumannii (CRAB) …

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia

GL Murray, K Tsyganov, XP Kostoulias… - The Journal of …, 2017 - academic.oup.com
Acinetobacter baumannii is a pathogen of major importance in intensive care units worldwide,
baumannii pathogenesis for the future development of novel targeted therapies. In this …

Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

…, NJ Mortman, Y Dai, M Cokol, S Syal, A Farinha… - Nature …, 2020 - nature.com
… Diagram outlines the multiple parallel Tn-seq fitness profiling experiments as described in “…
fitness of transposon mutants, we used previously constructed random banks of A. baumannii

Pathogenicity and virulence of Acinetobacter baumannii: Factors contributing to the fitness in healthcare settings and the infected host

M Lucidi, D Visaggio, A Migliaccio, G Capecchi… - Virulence, 2024 - Taylor & Francis
Acinetobacter baumannii is a common cause of healthcare-associated infections and hospital
outbreaks, particularly in … baumannii fitness during infection remains an open question. …

Relationship Between Different Resistance Mechanisms and Virulence in Acinetobacter baumannii

P Espinal, A Pantel, D Rolo, S Marti… - Microbial Drug …, 2019 - liebertpub.com
… Although colistin resistance may suggest a fitness and virulence cost for bacteria,52 our results
Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: a case …

Colistin and Carbapenem-Resistant Acinetobacter baumannii Aci46 in Thailand: Genome Analysis and Antibiotic Resistance Profiling

N Thadtapong, S Chaturongakul, S Soodvilai, P Dubbs - Antibiotics, 2021 - mdpi.com
… uses combined strategies, namely, bacterial fitness and pathogenicity, to cause disease in
… Genotypic characteristics underlying the antibiotic resistance profile of Aci46 are found on its …

… of colistin resistance without loss of fitness and virulence after prolonged colistin administration in a patient with extensively drug-resistant Acinetobacter baumannii

E Durante-Mangoni, M Del Franco, R Andini… - … and infectious disease, 2015 - Elsevier
baumannii strains belonged to the same major PFGE profile A but showed distinct PFGE
subtypes A, A1, and A2. The above data suggest also that colistin-R strains of PFGE type A1 …