Acinetobacter baumannii: Mechanisms of Resistance, Multiple ß-Lactamases
L Poirel, P Nordmann - Acinetobacter Biology and Pathogenesis, 2008 - Springer
Acinetobacter baumannii produces naturally an AmpC-type cephalosporinase, normally
expressed at a basal level, which does not reduce the efficacy of expanded-spectrum
cephalosporins (Bou and Martinez-Beltran, 2000). The AmpC variants identified from A.
baumannii strains have been named ADC-type (Acinetobacter derived cephalosporinase)
enzymes (Hujer et al., 2005). They hydrolyze amino-penicillins and first-, second-and third-
generation cephalosporins; they do not confer resistance to ceftazidime when the …
expressed at a basal level, which does not reduce the efficacy of expanded-spectrum
cephalosporins (Bou and Martinez-Beltran, 2000). The AmpC variants identified from A.
baumannii strains have been named ADC-type (Acinetobacter derived cephalosporinase)
enzymes (Hujer et al., 2005). They hydrolyze amino-penicillins and first-, second-and third-
generation cephalosporins; they do not confer resistance to ceftazidime when the …
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