Acinetobacter baumannii Antibiotic Resistance Mechanisms

I Kyriakidis, E Vasileiou, ZD Pana, A Tragiannidis - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is … action is unknown, the hydrophobic tail of polymyxins seems
to be crucial for the induction of membrane damage, suggesting a detergent-like mode of action

Systematic analyses identify modes of action of ten clinically relevant biocides and antibiotic antagonism in Acinetobacter baumannii

L Li, FL Short, KA Hassan, V Naidu, A Pokhrel… - Nature …, 2023 - nature.com
… , Acinetobacter baumannii, … baumannii fitness in biocides, we confirmed that sub-inhibitory
concentrations of the biocides that dissipate membrane potential can promote A. baumannii

Antibacterial and Antibiofilm Activity and Mode of Action of Magainin 2 against Drug-Resistant Acinetobacter baumannii

MK Kim, NH Kang, SJ Ko, J Park, E Park… - International Journal of …, 2018 - mdpi.com
Acinetobacter baumannii. Magainin 2 showed excellent antibacterial activity against A.
baumanniibaumannii strains exposed to magainin 2. We confirmed the mechanism of magainin …

Synergistic Activity of Capsaicin and Colistin Against Colistin-Resistant Acinetobacter baumannii: In Vitro/Vivo Efficacy and Mode of Action

T Guo, M Li, X Sun, Y Wang, L Yang, H Jiao… - Frontiers in …, 2021 - frontiersin.org
Acinetobacter baumannii is an opportunistic pathogen … unrelated colistin-resistant
Acinetobacter baumannii strains in vitro … baumannii. A mouse bacteremia model confirmed the in …

Antibacterial activity and mode of action of Mentha arvensis ethanol extract against multidrug-resistant Acinetobacter baumannii

L Zhang, S Xu, W Liang, J Mei, Y Di, H Lan… - Tropical Journal of …, 2015 - ajol.info
Purpose: To evaluate the antibacterial effect of ethanol extract of Mentha arvensis against
multi-drug resistant Acinetobacter baumannii using liquid chromatography–mass spectrometry …

Bacterial cytological profiling as a tool to study mechanisms of action of antibiotics that are active against Acinetobacter baumannii

HH Htoo, L Brumage, V Chaikeeratisak… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… An increasing number of multidrug-resistant Acinetobacter baumannii (MDR-AB) infections
… The establishment of methods to elucidate the mechanism of action (MOA) of A. baumannii-…

… Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action

A Oddo, TT Thomsen, S Kjelstrup, C Gorey… - Antimicrobial Agents …, 2016 - Am Soc Microbiol
Multiple strains of Acinetobacter baumannii have developed multidrug resistance (MDR),
leaving colistin as the only effective treatment. The cecropin-α–melittin hybrid BP100 (…

Exploring the Antimicrobial Action of Quaternary Amines against Acinetobacter baumannii

GA Knauf, AL Cunningham, MI Kazi, IM Riddington… - MBio, 2018 - Am Soc Microbiol
… our understanding of their mode of action is incomplete. Here we describe disruption of
bacterial proteostasis as an unrecognized action of QAC antimicrobial action and uncover the …

… rifabutin against 293 contemporary carbapenem-resistant Acinetobacter baumannii clinical isolates and characterization of rifabutin mode of action and resistance mechanisms

V Trebosc, B Schellhorn, J Schill… - Journal of …, 2020 - academic.oup.com
… potent activity against Acinetobacter baumannii in nutrient-limited … is carbapenem-resistant
Acinetobacter baumannii, against … baumannii when tested in the nutrient-limited Roswell Park …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible …
baumannii, few antibiotics are effective for treating infections caused by this pathogen. To …