Pre-treatment with P2Y12 inhibitors in ACS patients: who, when, why, and which agent?

D Sibbing, A Kastrati, PB Berger - European heart journal, 2016 - academic.oup.com
… for the P2Y12 inhibitors. The onset of action is significantly delayed in STEMI and cardiogenic
shock patients for all oral P2Y12 inhibitors. Following intestinal absorption, ticagrelor does …

Meta-analysis comparing P2Y12 inhibitors in acute coronary syndrome

L Baldetti, F Melillo, F Moroni, G Gallone… - The American journal of …, 2020 - Elsevier
… Conversely, we examined efficacy and safety of P2Y 12 inhibitors in a large cohort of patients
using standard drug dosages in a population exclusively composed by ACS patients and …

Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52 816 Patients From 12 Randomized Trials

EP Navarese, SU Khan, M Kołodziejczak, J Kubica… - Circulation, 2020 - Am Heart Assoc
… available on oral P2Y 12 inhibitors in acute coronary syndrome. We aimed to evaluate …
safety profile of prasugrel, ticagrelor, and clopidogrel in acute coronary syndrome by a meta-…

Potent P2Y12 inhibitors versus Clopidogrel in elderly patients with acute coronary syndrome: Systematic review and meta-analysis

T Fujisaki, T Kuno, T Ando, A Briasoulis, H Takagi… - American Heart …, 2021 - Elsevier
… on ischemic and bleeding events in elderly ACS patients has been … optimal P2Y12 inhibitor
in elderly patients with ACS by assessing the efficacy and safety of potent P2Y12 inhibitors

Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials

M Galli, S Benenati, F Franchi, F Rollini… - European heart …, 2022 - academic.oup.com
inhibitors currently recommended for the treatment of patients with ACS (clopidogrel, prasugrel,
and ticagrelor… standard selection of P2Y 12 inhibitors among patients with ACS were also …

The timing of P2Y12 inhibitor initiation in the treatment of ACS? Does the evidence exist in this era?

H Golwala, DL Bhatt - Progress in Cardiovascular Diseases, 2018 - Elsevier
… The goal in this subset of ACS patients would be to achieve adequate platelet inhibition
and prevention of further platelet aggregation and thrombosis while awaiting invasive …

[HTML][HTML] Efficacy and safety of newer P2Y12 inhibitors for acute coronary syndrome: a network meta-analysis

Y Fei, CK Lam, BMY Cheung - Scientific Reports, 2020 - nature.com
ticagrelor for ACS patients at moderate to high ischemic risk regardless of the initial treatment,
but prasugrel for ACS patients … 12 inhibitors with that of clopidogrel in patients with ACS, …

[HTML][HTML] Pre-Treatment With Oral P2Y12 Inhibitors in Acute Coronary Syndromes Without ST-Segment Elevation: The Saga Continues

D Capodanno, DJ Angiolillo - Journal of the American College of …, 2019 - jacc.org
ACS patients undergoing ad hoc PCI who were not pre-treated with a P2Y 12 inhibitor, ticagrelor
… tested with ticagrelor in the context of a randomized study of non–ST-segment elevation …

Efficacy and safety of potent platelet P2Y12 receptor inhibitors in elderly versus nonelderly patients with acute coronary syndrome: A systematic review and meta …

G Tarantini, D Ueshima, G D'Amico, G Masiero… - American heart …, 2018 - Elsevier
… use of more potent P2Y12 inhibitors led to similar relative benefits in reducing the composite
efficacy outcome of death, MI, or stroke in elderly and nonelderly ACS patients but also to …

P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised controlled trials

M Valgimigli, F Gragnano, M Branca, A Franzone… - Bmj, 2021 - bmj.com
… Despite supportive evidence from subgroups of large trials after acute coronary syndrome
for clopidogrel or ticagrelor,29 30 a DAPT regimen remains inconsistently implemented in …