… polymerase I. Actin is directly associated with RNA polymerase I (Pol I), regardless of
whether Pol I is engaged in transcription, and nuclear myosin 1 (NM1) interacts with …

… We do not know how actin contributes to the basal transcription process. Nor do we know
whether all three RNA polymerases use actin in the same manner. It has been proposed, …

… transcription from the human U6 snRNA gene is reconstituted with recombinant factors and
purified RNA polymerase … III contains associated β-actin, and β-actin localizes to an active U6 …

… restricted to the transcription of mRNA-coding genes by Pol II, but to be used by all three
classes of nuclear RNA polymerases. In support of this, both NMI and actin have been shown to …

… actin in RNA polymerase II transcription in mammalian cells. Both in vivo and in … transcription
assays in the presence of anti-actin antibodies showed that RNA polymerase II transcription …

… We discuss a general model for actin in RNA polymerase II transcription whereby actin works
as a conformational switch in conjunction with specific adaptors to facilitate the remodeling …

… and NM1 in transcription. Here we show that actin and NM1 act in concert to promote
RNA polymerase I (Pol I) transcription. Drugs that prevent …

… However, how transcription is regulated under these scenarios is largely unknown. Here, …
role of nuclear actin in transcriptional regulation. The RNA-seq data reveal that nuclear actin is …

… actin into persistent nuclear actin filaments affected transcription by RNA polymerase II.
Nuclear filaments impaired nuclear actin dynamics by polymerizing and sequestering nuclear …

… Actin is associated with all three nuclear RNA polymerases and acts in concert with nuclear
… that actin is a constitutive component of the RNA polymerase II (pol II) transcription machinery…