Comparative cardiovascular and cerebrovascular safety of inhaled long‐acting bronchodilators in patients with chronic obstructive pulmonary disease: a population …

YH Dong, CH Chang, JJ Gagne… - … : The Journal of …, 2016 - Wiley Online Library
… similar cardiovascular and cerebrovascular safety of LABA … with inhaled long-acting
bronchodilator combination therapy. … of cardiovascular and cerebrovascular mortality and …

Long-acting bronchodilator initiation in COPD and the risk of adverse cardiopulmonary events: a population-based comparative safety study

S Suissa, S Dell'Aniello, P Ernst - Chest, 2017 - Elsevier
… In all, the long-acting bronchodilators recommended as first-… comparable cardiovascular and
cerebrovascular safety profiles. In … a safety advantage to tiotropium as the initial long-acting

Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events

S Suissa, S Dell'Aniello, P Ernst - European Respiratory …, 2017 - Eur Respiratory Soc
… cardiovascular and cerebrovascular safety of adding a second long-acting bronchodilator in
… , we assessed the comparative safety of adding a second long-acting bronchodilator (either …

[HTML][HTML] Risk of adverse cardiovascular events with use of inhaled long-acting bronchodilators in management of chronic obstructive pulmonary disease

MT Wang, JH Lai, CL Tsai, JT Liou - journal of food and drug analysis, 2019 - Elsevier
… the cardiovascular safety of inhaled long-acting bronchodilators. … Cardio- and cerebrovascular
safety, including MACE, AF or … cardio- and cerebrovascular events across three groups. …

Safety considerations with dual bronchodilator therapy in COPD: an update

MG Matera, P Rogliani, L Calzetta, M Cazzola - Drug safety, 2016 - Springer
Combining a long-acting β 2 -agonist (LABA) with a long-acting anti-muscarinic agent (LAMA)
provides synergistic benefit on airway smooth muscle relaxation, which may have major …

[HTML][HTML] Cardio-and cerebrovascular safety of indacaterol vs formoterol, salmeterol, tiotropium and placebo in COPD

H Worth, KF Chung, JM Felser, H Hu, P Rueegg - Respiratory medicine, 2011 - Elsevier
… In conclusion, the CCV safety profile of indacaterol compares favourably with existing
long-acting bronchodilator treatments. The acceptable CCV safety profile of indacaterol in a …

The safety of dual bronchodilation on cardiovascular serious adverse events in COPD

P Rogliani, J Ora, MG Matera, M Cazzola… - … on Drug Safety, 2018 - Taylor & Francis
safety end points for the GLY/IND FDC, which had a safety … risk of cardiovascular and
cerebrovascular SAEs, death, and … a second long-acting bronchodilator agent did not increase …

Risk of Cardiovascular and Cerebrovascular Events in COPD Patients Treated With Long-Acting β2-Agonist Combined With a Long-Acting Muscarinic or Inhaled …

JC Samp, MJ Joo, GT Schumock… - Annals of …, 2017 - journals.sagepub.com
acting bronchodilator; however, the cause of death was not specific to cardiovascular or
cerebrovascular … Therefore, the aim of this study is to examine the real-world CCV safety of LABA/…

Randomized controlled trials and real-world observational studies in evaluating cardiovascular safety of inhaled bronchodilator therapy in COPD

P Kardos, S Worsley, D Singh… - … journal of chronic …, 2016 - Taylor & Francis
… We examine what is already known regarding the CV and cerebrovascular safety of
LAMA/LABA … safety of inhaled long-acting bronchodilators in individuals with chronic obstructive …

The safety of anticholinergic bronchodilators for the treatment of chronic obstructive pulmonary disease

DP Tashkin - Expert Opinion on Drug Safety, 2015 - Taylor & Francis
safety of tiotropium have not confirmed these safety concerns. Because of the relatively limited
amount of safety data for the newer long-acting … accumulate additional safety information …