[HTML][HTML] Comparative cardiovascular safety of LABA/LAMA FDC versus LABA/ICS FDC in patients with chronic obstructive pulmonary disease: a population-based …

CY Chen, SW Pan, CC Hsu, JJ Liu, H Kumamaru… - Respiratory …, 2023 - Springer
… Long-acting bronchodilators, including long-acting β 2 agonists (LABA) and long-acting
muscarinic … safety of dual bronchodilator treatment strategies in COPD in the real-world settings. …

Chronic obstructive pulmonary disease: an evidence-based approach to treatment with a focus on anticholinergic bronchodilation

NJ Gross - Mayo Clinic Proceedings, 2008 - Elsevier
… an inhaled short-acting bronchodilator can be prescribed for … due to arthritis, cerebrovascular
disease, or poor vision. … The tiotropium safety database includes data on 2159 person…

Comparison of inhaled long-acting β-agonist and anticholinergic effectiveness in older patients with chronic obstructive pulmonary disease: a cohort study

A Gershon, R Croxford, T To, MB Stanbrook… - Annals of internal …, 2011 - acpjournals.org
… heart disease, cardiac arrhythmias, or cerebrovascular disease). … Research is also needed
to examine the relative safety … first use of a long-acting bronchodilator, a majority of patients in …

[HTML][HTML] Cardiovascular safety of mometasone/indacaterol and mometasone/indacaterol/glycopyrronium once-daily fixed-dose combinations in asthma: pooled …

E Scosyrev, R van Zyl-Smit, H Kerstjens, C Gessner… - Respiratory …, 2021 - Elsevier
… Cardio-/cerebrovascular (CCV) event frequencies were … function are likely to receive a
second bronchodilator or a fixed-dose … safety findings from observational studies of long-acting

Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk

RD Brook, JA Anderson, PMA Calverley, BR Celli… - Heart, 2017 - heart.bmj.com
… . Cardiovascular safety of inhaled long-acting bronchodilators in individuals with chronic
obstructive pulmonary disease. JAMA Intern Med 2013;173:1175–85.doi:10.1001/…

Safety of chronic obstructive pulmonary disease medications: a primary care perspective

NA Hanania - Postgraduate Medicine, 2011 - Taylor & Francis
… -acting bronchodilators, whereas according to their pharmacological properties, bronchodilators
… Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a …

Dual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study

DA Mahler, M Decramer, A D'Urzo… - European …, 2014 - Eur Respiratory Soc
… Use of long-acting bronchodilators or short-acting muscarinic … Safety was assessed in the
safety population, which … Serious cardio- and cerebrovascular adverse events were infrequent …

[HTML][HTML] Pooled safety analysis of the fixed-dose combination of indacaterol and glycopyrronium (QVA149), its monocomponents, and tiotropium versus placebo in …

JA Wedzicha, R Dahl, R Buhl, A Schubert-Tennigkeit… - Respiratory …, 2014 - Elsevier
… long-acting bronchodilators at therapeutic … cerebrovascular (CCV) mortality or morbidity
in patients with COPD [6], [7]. The efficacy and safety of free-dose combinations of long-acting

Current controversies in the stepping up and stepping down of inhaled therapies for COPD at the patient level

JL Lopez‐Campos, L Carrasco Hernández… - …, 2018 - Wiley Online Library
… to single bronchodilation, with a special focus on safety. We … have established long-acting
bronchodilators (LABD) as the … difference in the risk of cerebrovascular events. Therefore, …

Effect of aclidinium bromide on major cardiovascular events and exacerbations in high-risk patients with chronic obstructive pulmonary disease: the ASCENT-COPD …

RA Wise, KR Chapman, BM Scirica, DL Bhatt… - Jama, 2019 - jamanetwork.com
bronchodilation in patients with COPD, there is controversy surrounding their cardiovascular
safety… Patients were required to have at least 1 of the following: cerebrovascular disease (eg…