Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

A Manoharan, PM Short, WJ Anderson, BJ Lipworth - Lung, 2014 - Springer
… assess the impact of long-acting bronchodilator therapy and associated exposure to inhaled
… to long-acting bronchodilators only and 3,510 to long-acting bronchodilators plus ICS. 1,372 …

A new user cohort study comparing the safety of long-acting inhaled bronchodilators in COPD

M Jara, C Wentworth, S Lanes - BMJ open, 2012 - bmjopen.bmj.com
… added a different long-acting bronchodilator thereby terminating study participation, a lower
… of a long-acting bronchodilator prior to the administrative end of the study (58% compared …

Characteristics of patients with COPD newly prescribed a long-acting bronchodilator: a retrospective cohort study

KE Wurst, S St Laurent, H Mullerova… - International Journal of …, 2014 - Taylor & Francis
… This study aimed to characterize patients with chronic obstructive pulmonary disease (COPD)
newly prescribed a long-acting bronchodilator (LABD), and to assess changes in …

Comparative safety of long-acting inhaled bronchodilators: a cohort study using the UK THIN primary care database

M Jara, SF Lanes, C Wentworth, C May, S Kesten - Drug safety, 2007 - Springer
… -acting bronchodilators, we conducted a cohort study. Specifically, the study compared
the safety of the only approved long-acting … the single-ingredient long-acting β-agonists (LABAs) …

Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

PM Short, SIW Lipworth, DHJ Elder, S Schembri… - Bmj, 2011 - bmj.com
… Current COPD management guidelines advocate a stepwise approach using long acting
bronchodilators (including β agonists) and inhaled corticosteroids to reduce exacerbations and …

Risk of pneumonia with inhaled corticosteroid versus long-acting bronchodilator regimens in chronic obstructive pulmonary disease: a new-user cohort study

RL DiSantostefano, T Sampson, HV Le, D Hinds… - PLoS …, 2014 - journals.plos.org
… years) in the present study for the ICS-containing and LABD cohorts, respectively (48.7
and 30.9) are lower than reported in the 3-year TORCH study of FP/salmeterol combination (84–…

Comparison of inhaled long-acting β-agonist and anticholinergic effectiveness in older patients with chronic obstructive pulmonary disease: a cohort study

A Gershon, R Croxford, T To, MB Stanbrook… - Annals of internal …, 2011 - acpjournals.org
… understanding of the comparative efficacy of long-acting bronchodilators in COPD, it is important
to … the two studies--most notably differences in study population, design, and outcomes. …

… and cerebrovascular safety of inhaled long‐acting bronchodilators in patients with chronic obstructive pulmonary disease: a population‐based cohort study

YH Dong, CH Chang, JJ Gagne… - … : The Journal of …, 2016 - Wiley Online Library
studies in real-world settings have assessed the comparative safety of inhaled long-acting
bronchodilator … Therefore, we conducted a population-based retrospective cohort study to …

Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study

M Wilchesky, P Ernst, JM Brophy, RW Platt, S Suissa - Chest, 2012 - Elsevier
Bronchodilator medications are central to the symptomatic … a short-acting bronchodilator,
whether it be a β 2 -agonist, an anticholinergic, or a combination of these two bronchodilators, …

Use patterns of long-acting bronchodilators in routine COPD care: the OUTPUL study

…, M Davoli, OUTPUL Study Group - COPD: Journal of …, 2014 - Taylor & Francis
… any study drug of interest (long-acting bronchodilators or ICS)… , and short-acting anticholinergic
drugs were frequently used. … with the ECLIPSE study (Citation32), in our cohort we found …