An evidence-based review of the mechanism of action, efficacy, and safety of biologic therapies in the treatment of psoriasis and psoriatic arthritis

EA Brezinski, AW Armstrong - Current Medicinal Chemistry, 2015 - ingentaconnect.com
… of efficacious and safe systemic therapies for the treatment of moderate-to-severe psoriasis
and active psoriatic arthritis… proposed molecular mechanisms of action, efficacy, and safety of …

Updated therapies for the management of psoriatic arthritis

A Toussi, N Maverakis, ST Le, S Sarkar… - Clinical …, 2020 - Elsevier
Psoriatic arthritis (PsA) is a large volume of our clinical practice and its management can be
challenging. Traditional DMARDs have been used over last six decades and observational …

… treatment of psoriatic arthritis: a systematic literature research for the 2019 update of the EULAR recommendations for the management of psoriatic arthritis

A Kerschbaumer, JS Smolen, M Dougados… - Annals of the …, 2020 - ard.bmj.com
… Figure 2 depicts a crude summary on the efficacy results of interventions by mode of action
and disease domain. Most RCTs were regarded to have low RoB, while unclear RoB was …

EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update

L Gossec, X Baraliakos, A Kerschbaumer… - Annals of the …, 2020 - ard.bmj.com
… (EULAR) recommendations for the pharmacological treatment of psoriatic arthritis (PsA). …
are proposed as initial therapy; for patients with arthritis and poor prognostic factors, such as …

[HTML][HTML] Switching biologics in the treatment of psoriatic arthritis

JF Merola, B Lockshin, EA Mody - Seminars In Arthritis And Rheumatism, 2017 - Elsevier
… patients, but bDMARDs with different mechanisms of action may be superior alternatives. …
) have either demonstrated limited evidence of efficacy or failed to demonstrate consistent …

[PDF][PDF] Treatment of psoriatic arthritis: management recommendations

L Gossec, JS Smolen - Clin Exp Rheumatol, 2015 - clinexprheumatol.org
… with disease modifying drugs -- comparison of drugs and adverse reactions. J Rheumatol …
Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the …

Is there a need for new agents with novel mechanisms of action in psoriatic arthritis?

C Orr, DJ Veale - Annals of the Rheumatic Diseases, 2014 - ard.bmj.com
… of efficacy in treating spinal symptoms where conventional DMARDs show little efficacy.6 …
patients in Europe, and all show equivalent efficacy in the treatment of joint disease.1 ,7 – 9 …

[HTML][HTML] Targeted therapies in psoriatic arthritis—an update

S Sundanum, C Orr, D Veale - International Journal of Molecular Sciences, 2023 - mdpi.com
… the targeted therapies discussed in this review with their corresponding mode of action. …
efficacy and safety of implementing dual cytokine inhibition in the setting of psoriatic arthritis [32]. …

Efficacy of tofacitinib in the treatment of psoriatic arthritis: a systematic review

J Gratacos Masmitja, CM Gonzalez Fernandez… - Advances in …, 2021 - Springer
… Therapeutic approaches for psoriatic arthritis (PsA) include non-… on efficacy of tofacitinib
in the treatment of PsA, giving special attention to non-skin manifestations (peripheral arthritis, …

… treatment of psoriatic arthritis: a systematic literature review for the 2015 update of the EULAR recommendations for the management of psoriatic arthritis

S Ramiro, JS Smolen, R Landewé… - Annals of the …, 2016 - ard.bmj.com
… /abstracts focused on 3 drugs with new modes of action: ustekinumab (UST), secukinumab
(… of the present review (psoriatic arthritis long-term assessment of clinical efficacy; PALACE-1)…