… role of NLRP3 in the maintenance of immune tolerance and epithelial barrier … NLRP3
inflammasome during intestinal inflammation is associated with a breakdown of intestinal immune …

… Irg1 establishes LPS-mediated tolerance to signal 2 of NLRP3 inflammasome activation
We previously demonstrated that itaconate inhibits NLRP3 inflammasome activation in …

… NEAT1 knockdown in DCs can induce immune tolerance in models of experimental … immune
cascade 28 , 29 . Several studies have shown that activation of the NLRP3 inflammasome …

… The activated NLRP3 inflammasome can eliminate … vital upstream events in NLRP3
inflammasome activation. … of immunological tolerance and aberrant autoreactive immune …

… process are sufficient to activate the NLRP3 inflammasome. In some cases, viral proteins
also regulate the activation of the NLRP3 inflammasome. The inflammasome-induced cell …

… of the assembly and activation of the NLRP3 inflammasome, a central molecule at the
crossroads of each pathway implicated in NLRP3 inflammasome activation has yet to be identified…

… Gain-of-function mutations in NLRP3 that increase IL-1β secretion account for hereditary …
that the activation of the NLRP3 inflammasome within DCs is decisive for the immune response …

… In this study, IL-1β is activated by the NLRP3 inflammasome pathway and promotes the
breaking of the atherosclerotic plaques. When animals lacking the LDL receptor, already …

… The inflammatory responses elicited after modest activation of the NLRP3 inflammasome can
… Autoimmune diseases are complex and characterized by the loss of immune tolerance to …

… (PDA) is characterized by immune tolerance, which enables … Our data suggest that targeting
the NLRP3 inflammasome … pharmacologic inhibition of NLRP3 activation would be similarly …