… This prompted us to investigate the specific roles of PPARα, PPARβ/δ, and PPARγ in the
cardiac muscle cell with respect to the regulation of genes encoding proteins involved in energy …

… , PPARγ activation by glitazones and PPARα activation by … heart, steering cardiac energy
metabolism in cardiomyocytes… cell activation and adhesion and vascular smooth muscle cell …

… PPARβ/δ activation by GW501516 reduced the induction of the NF-κB target genes MCP-1
and TNF-α in human cardiac cells stimulated by palmitate and in the heart … cardiac myocytes …

… evidence that PPARγ protected cardiac myocytes from H 2 O … in the cardiomyocytes was
dependent upon the activation of … , respectively, suggesting the activation of caspase-3 during …

… cardiac myocytes, we have found that all three isoforms, PPARα, PPARβ/δ, and PPARγ, are
expressed in adult rat cardiac … , activation of PPARα and PPARβ/δ had no effect on cardiac …

… potent PPARβ/δ agonist GW0742 [22] and a specific PPARβ/… of receptor activation in H 2
O 2 -induced cardiac myocyte … We demonstrate that PPARβ/δ activation in cardiac myocytes …

… , GW0742 and L-165041) that activate PPARβ/δ at very low concentrations both in vivo and
… suggested that the PPARβ/δ ligand GW0742 protects cardiac myocytes from oxidative stress…

… PPARβ/δ activation in phenylephrine (PE)-induced hypertrophy in neonatal rat cardiac
myocytes … We found that activation of PPARβ/δ inhibits PE-induced hypertrophy and LPS-induced …

… In contrast to PPARγ, which is adipose enriched, PPARβ/δ is highly expressed in cardiac
myocytes, … programs were activated in the MHC-PPARβ/δ mice, given the lack of an observed …

… By transient transfection of neonatal cardiac myocytes using the PPAR-responsive …
cardiomyocytes. These studies revealed that PPARα and PPARβ/δ ligands were both able to activate …