… High HTLV-1 proviral load (PVL) is mainly found in infected … of PVL in the activation of T
lymphocytes of asymptomatic … Regarding the subpopulation of CD8 + T cells, our study showed a …

… This interpretation can explain our findings and is also consistent with the finding of roughly
similar amounts of proviral DNA in peripheral blood mononuclear cells from people infected …

… aberrant immune activation in CD8 + and CD4 + T cells can … increased activation, exhaustion,
and proliferation of T cells … levels of chronic cellular immune activation. This is supported …

… with hemophilia have activated, Gagspecific cytotoxic CD8 T lymphocytes in the peripheral
… provirus load was independent of the CD4 T cell count. As would be expected, proviral DNA …

… CD8 + T cells is positively correlated with the proviral load of … cells play an active role in
controlling HTLV-1 proviral load, or … for T cells that reduces the threshold of T cell activation (42). …

… Jurkat cells using activated human primary CD4 + T cells as a positive control. We found
that Jurkat cells displayed very low levels of TLR2 mRNA compared to activated CD4 + T cells (…

… Thus, our finding of an increase in memory (CD45RO) and activated (HLA-DR) CD4 + T
cells in the joint fluid of an HTLV-1 carrier with RA supports the hypothesis of a pathogenic …

… T-cell lymphotropic virus type I proviral load in cerebrospinal fluid cells from human T-cell …
It has been demonstrated that activated T cells migrate into the CNS, irrespective of antigen …

… Proviral HIV-1 DNA. To test the … in vitro activated HIV controller CD4 + T cells is the result
of the low frequency of infected CD4 + cells in the peripheral blood, we measured HIV proviral …

… as infection of these cells is very … provirus in activated effector T lymphocytes. We observed
that for every virus producing cell there is at least one other cell harboring a latent provirus, …