Active promoters give rise to false positive 'Phantom Peaks' in ChIP-seq experiments
… We obtained robust and high-quality ChIP-seq profiles by all accepted modENCODE …
ChIP-seq profiles suggested co-localization of the two remodeling factors at the active promoter …
ChIP-seq profiles suggested co-localization of the two remodeling factors at the active promoter …
ChIP-seq accurately predicts tissue-specific activity of enhancers
… be active enhancers … promoters are 2.4-fold enriched overall in p300-binding sites (P <
0.05, Fig. 5a). In total, 14% of all forebrain p300 peaks are located within 101 kb from a promoter …
0.05, Fig. 5a). In total, 14% of all forebrain p300 peaks are located within 101 kb from a promoter …
ChIP-Seq data reveal nucleosome architecture of human promoters
CD Schmid, P Bucher - Cell, 2007 - cell.com
… active promoters. Our results further suggest that ChIP-Seq may be an effective alternative
technique for genome-wide promoter mapping, complementing methods based on the 5′ tag …
technique for genome-wide promoter mapping, complementing methods based on the 5′ tag …
Integrating ChIP-seq with other functional genomics data
S Jiang, A Mortazavi - Briefings in functional genomics, 2018 - academic.oup.com
… , which are then interpreted as chromatin states based on the chromatin profile and gene
annotations, such as active promoter/enhancer, transcriptional elongation or repressive states. …
annotations, such as active promoter/enhancer, transcriptional elongation or repressive states. …
ChIP-Seq identification of weakly conserved heart enhancers
MJ Blow, DJ McCulley, Z Li, T Zhang, JA Akiyama… - Nature …, 2010 - nature.com
… active developmental enhancers 16,17,18,19 . To obtain an initial genome-wide set of candidate
enhancer sequences active in the heart, we performed p300 ChIP-Seq … likely promoter …
enhancer sequences active in the heart, we performed p300 ChIP-Seq … likely promoter …
Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond
… as a mark of active gene transcription. Tiwari et al. showed by genome-wide ChIP-seq
analysis that c-Jun NH2-terminal kinase (JNK) binds to a large set of active promoters during the …
analysis that c-Jun NH2-terminal kinase (JNK) binds to a large set of active promoters during the …
[PDF][PDF] Application of ChIP-Seq and related techniques to the study of immune function
DL Northrup, K Zhao - Immunity, 2011 - cell.com
… H3K4me3, associated with active promoters, is highly localized to a few nucleosomes
around promoter regions, probably deposited by complexes that directly interact with sequence …
around promoter regions, probably deposited by complexes that directly interact with sequence …
Identifying dispersed epigenomic domains from ChIP-Seq data
… For example, H3K4me3 is usually associated with active promoters, and occurs only at
nucleosomes close to transcription start sites (TSSs). On the other hand, many histone …
nucleosomes close to transcription start sites (TSSs). On the other hand, many histone …
Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages
… These loci show evidence of open chromatin and H3K4me1 but do not resemble active
promoters or enhancers. Analysis of the ChIP-seq data identified a set of three transcription …
promoters or enhancers. Analysis of the ChIP-seq data identified a set of three transcription …
Z-DNA-forming sites identified by ChIP-Seq are associated with actively transcribed regions in the human genome
… The association of Z-DNA with active transcription was … as sequence composition, and is
associated with active transcription in … Because many of our ZFSs were detected in the promoter …
associated with active transcription in … Because many of our ZFSs were detected in the promoter …
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