Active promoters give rise to false positive 'Phantom Peaks' in ChIP-seq experiments

D Jain, S Baldi, A Zabel, T Straub… - Nucleic acids …, 2015 - academic.oup.com
… We obtained robust and high-quality ChIP-seq profiles by all accepted modENCODE …
ChIP-seq profiles suggested co-localization of the two remodeling factors at the active promoter

ChIP-seq accurately predicts tissue-specific activity of enhancers

A Visel, MJ Blow, Z Li, T Zhang, JA Akiyama, A Holt… - Nature, 2009 - nature.com
… be active enhancers … promoters are 2.4-fold enriched overall in p300-binding sites (P <
0.05, Fig. 5a). In total, 14% of all forebrain p300 peaks are located within 101 kb from a promoter

ChIP-Seq data reveal nucleosome architecture of human promoters

CD Schmid, P Bucher - Cell, 2007 - cell.com
active promoters. Our results further suggest that ChIP-Seq may be an effective alternative
technique for genome-wide promoter mapping, complementing methods based on the 5′ tag …

Integrating ChIP-seq with other functional genomics data

S Jiang, A Mortazavi - Briefings in functional genomics, 2018 - academic.oup.com
… , which are then interpreted as chromatin states based on the chromatin profile and gene
annotations, such as active promoter/enhancer, transcriptional elongation or repressive states. …

ChIP-Seq identification of weakly conserved heart enhancers

MJ Blow, DJ McCulley, Z Li, T Zhang, JA Akiyama… - Nature …, 2010 - nature.com
active developmental enhancers 16,17,18,19 . To obtain an initial genome-wide set of candidate
enhancer sequences active in the heart, we performed p300 ChIP-Seq … likely promoter

Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond

R Mundade, HG Ozer, H Wei, L Prabhu, T Lu - Cell Cycle, 2014 - Taylor & Francis
… as a mark of active gene transcription. Tiwari et al. showed by genome-wide ChIP-seq
analysis that c-Jun NH2-terminal kinase (JNK) binds to a large set of active promoters during the …

[PDF][PDF] Application of ChIP-Seq and related techniques to the study of immune function

DL Northrup, K Zhao - Immunity, 2011 - cell.com
… H3K4me3, associated with active promoters, is highly localized to a few nucleosomes
around promoter regions, probably deposited by complexes that directly interact with sequence

Identifying dispersed epigenomic domains from ChIP-Seq data

Q Song, AD Smith - Bioinformatics, 2011 - academic.oup.com
… For example, H3K4me3 is usually associated with active promoters, and occurs only at
nucleosomes close to transcription start sites (TSSs). On the other hand, many histone …

Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages

X Lan, H Witt, K Katsumura, Z Ye, Q Wang… - Nucleic acids …, 2012 - academic.oup.com
… These loci show evidence of open chromatin and H3K4me1 but do not resemble active
promoters or enhancers. Analysis of the ChIP-seq data identified a set of three transcription …

Z-DNA-forming sites identified by ChIP-Seq are associated with actively transcribed regions in the human genome

SI Shin, S Ham, J Park, SH Seo, CH Lim, H Jeon… - DNA …, 2016 - academic.oup.com
… The association of Z-DNA with active transcription was … as sequence composition, and is
associated with active transcription in … Because many of our ZFSs were detected in the promoter