[PDF][PDF] Opioids and neuropathic pain
HS Smith - Pain physician, 2012 - painphysicianjournal.com
… Efficacy of mu-opioid agonists in the treatment of evoked neuropathic pain: Systematic review
of … Controlled-release oxycodone--a therapeutic option for severe neuropathic pain. Two …
of … Controlled-release oxycodone--a therapeutic option for severe neuropathic pain. Two …
Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials
E Eisenberg, ED McNicol, DB Carr - Jama, 2005 - jamanetwork.com
… prescribing of opioids to patients with neuropathic pain, we … efficacy of opioid agonists in
relieving neuropathic pain? and (2… of acute exposure to opioids in 267 patients with neuropathic …
relieving neuropathic pain? and (2… of acute exposure to opioids in 267 patients with neuropathic …
Bifunctional peptide-based opioid agonist–nociceptin antagonist ligands for dual treatment of acute and neuropathic pain
K Guillemyn, J Starnowska, C Lagard… - Journal of medicinal …, 2016 - ACS Publications
… , and agonist properties at the opioid receptors and antagonist properties for NOP. (52, 53) …
of dual opioid–nociceptin ligands for the treatment of chronic and neuropathic pain, which …
of dual opioid–nociceptin ligands for the treatment of chronic and neuropathic pain, which …
Why mu‐opioid agonists have less analgesic efficacy in neuropathic pain?
M Martínez‐Navarro, R Maldonado… - … Journal of Pain, 2019 - Wiley Online Library
… of opioid monotherapy in neuropathic pain and analyses the reasons of this reduced
effectiveness. Opioid agonists … Indeed, some severe neuropathic pain conditions are still treated …
effectiveness. Opioid agonists … Indeed, some severe neuropathic pain conditions are still treated …
Dual alleviation of acute and neuropathic pain by fused opioid agonist-neurokinin 1 antagonist peptidomimetics
C Betti, J Starnowska, J Mika, J Dyniewicz… - ACS Medicinal …, 2015 - ACS Publications
… opioid agonist-NK1 antagonist hybrids, is often dependent on the relative potency at the two
target receptors… hybrid opioid-NK1 ligands, in which potent opioid agonist pharmacophores …
target receptors… hybrid opioid-NK1 ligands, in which potent opioid agonist pharmacophores …
Local peripheral effects of μ-opioid receptor agonists in neuropathic pain in rats
I Obara, R Przewlocki, B Przewlocka - Neuroscience letters, 2004 - Elsevier
… neuropathic pain may be attenuated by higher doses (in comparison with those effective in
acute pain) of … effects, and validate the role of peripheral opioid receptors in neuropathic pain. …
acute pain) of … effects, and validate the role of peripheral opioid receptors in neuropathic pain. …
The role of δ-opioid receptor subtypes in neuropathic pain
J Mika, R Przewłocki, B Przewłocka - European journal of pharmacology, 2001 - Elsevier
… -opioid receptor agonists and antagonist after their acute and chronic intrathecal administration
in a neuropathic pain model … Agonists of both δ 1 - and δ 2 -opioid receptors exert strong …
in a neuropathic pain model … Agonists of both δ 1 - and δ 2 -opioid receptors exert strong …
Efficacy of mu-opioid agonists in the treatment of evoked neuropathic pain: systematic review of randomized controlled trials
E Eisenberg, ED McNicol, DB Carr - European Journal of Pain, 2006 - Elsevier
… -opioids in reducing spontaneous neuropathic pain (NP). However, relatively little is known
about their specific efficacy for evoked pain, … the efficacy of opioid agonists for the treatment of …
about their specific efficacy for evoked pain, … the efficacy of opioid agonists for the treatment of …
[HTML][HTML] A novel mu-delta opioid agonist demonstrates enhanced efficacy with reduced tolerance and dependence in mouse neuropathic pain models
… -DOR dual agonist given chronically in chronic neuropathic pain models has enhanced …
agonists did show high efficacy with acute administration in inflammatory and neuropathic pain…
agonists did show high efficacy with acute administration in inflammatory and neuropathic pain…
Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain
AT Podolsky, A Sandweiss, J Hu, EJ Bilsky, JP Cain… - Life sciences, 2013 - Elsevier
… a combination of acute and chronic pain models, we demonstrate here the efficacy of the
novel, non-peptidic opioid compound RV-Jim-C3 in treating neuropathic pain while lacking …
novel, non-peptidic opioid compound RV-Jim-C3 in treating neuropathic pain while lacking …
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