Ideal P2Y12 inhibitor in acute coronary syndrome: a review and current status

A Pradhan, A Tiwari, G Caminiti, C Salimei… - International Journal of …, 2022 - mdpi.com
… Hence, underscoring the central role of P2Y12 inhibitors for … the need for more potent P2Y12
inhibitors. We then describe the … We try to rationalize the use of different P2Y12 inhibitors in …

Meta-analysis of the relative efficacy and safety of oral P2Y12 inhibitors in patients with acute coronary syndrome

R Shah, A Rashid, I Hwang, THM Fan… - The American journal of …, 2017 - Elsevier
… with ACS, adding P2Y12 inhibitors to aspirin and other … Among the commonly used
oral P2Y12 inhibitors, ticagrelor … is the usual initiating event in acute coronary syndrome (ACS). …

Meta-analysis comparing P2Y12 inhibitors in acute coronary syndrome

L Baldetti, F Melillo, F Moroni, G Gallone… - The American journal of …, 2020 - Elsevier
inhibitor to reduce hard adverse events both at 30-day and 1-year follow-up. Antiplatelet
inhibition in acute coronary syndromes (… diphosphate receptor inhibitor has consistently reduced …

Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52 816 Patients From 12 Randomized Trials

EP Navarese, SU Khan, M Kołodziejczak, J Kubica… - Circulation, 2020 - Am Heart Assoc
… available on oral P2Y 12 inhibitors in acute coronary syndrome. We aimed to evaluate …
safety profile of prasugrel, ticagrelor, and clopidogrel in acute coronary syndrome by a meta-…

Timing of Oral P2Y12 Inhibitor Administration in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

G Tarantini, M Mojoli, F Varbella, R Caporale… - Journal of the American …, 2020 - jacc.org
… downstream and upstream oral P2Y 12 inhibitors administration strategies in patients
with non–ST-segment elevation acute coronary syndrome undergoing invasive treatment. …

Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials

M Galli, S Benenati, F Franchi, F Rollini… - European heart …, 2022 - academic.oup.com
inhibiting therapy using platelet function or genetic testing improves outcomes among patients
undergoing percutaneous coronary … -inhibiting therapy in acute coronary syndrome has …

P2Y12 inhibitors in acute coronary syndrome patients with renal dysfunction: an analysis from the RENAMI and BleeMACS projects

O De Filippo, F D'Ascenzo… - European Heart …, 2020 - academic.oup.com
… The aim of the present study was to establish the safety and efficacy profile of prasugrel
and ticagrelor in real-life acute coronary syndrome (ACS) patients with renal dysfunction. …

Efficacy and safety of newer P2Y12 inhibitors for acute coronary syndrome: a network meta-analysis

Y Fei, CK Lam, BMY Cheung - Scientific Reports, 2020 - nature.com
inhibitor recommended for the standard treatment and secondary prevention of ischemic
events in acute coronary syndrome (… of more potent, newer P2Y 12 inhibitors. Prasugrel, a third-…

Guided and unguided de-escalation from potent P2Y12 inhibitors among patients with acute coronary syndrome: a meta-analysis

AH Tavenier, R Mehran, M Chiarito… - European Heart …, 2022 - academic.oup.com
… of acute coronary syndromes (ACS). Currently, the guidelines recommend dual antiplatelet
therapy (DAPT) with aspirin and a potent P2Y 12 inhibitor (ie prasugrel or ticagrelor) for 12 …

Pretreatment With P2Y12 Inhibitors in Non–ST-Segment–Elevation Acute Coronary Syndrome Is Clinically Justified

M Valgimigli - Circulation, 2014 - Am Heart Assoc
ticagrelor 8 has resulted in further improvements of the ischemic outcomes. Finally, clopidogrel
9 and ticagrelor… top of aspirin in patients with acute coronary syndromes, regardless of the …