• Consider multisystem inflammatory syndrome (MIS-C) in children presenting with fever and abdominal symptoms—particularly if they develop conjunctivitis or rash—and refer to a paediatric emergency department for evaluation• MIS-C can have overlapping symptomatology with disease processes that require prompt treatment, such as sepsis, toxic shock syndrome, myocarditis, and meningitis. Therefore, consider initiation of empiric antibiotics and necessary evaluations if the patient develops cardiovascular or respiratory compromise, evidence of acute abdomen, or meningismus