Clinical applications and acute hepatotoxicity of intravenous amiodarone

X Huang, Y Yang, J Zhu, X Gao… - Journal of …, 2009 - journals.sagepub.com
Clinical data were collected from 1214 patients … acute hepatotoxicity associated with the
drug were examined. … is rare and potentially fatal; acute hepatotoxicity during intravenous …

Adenovirus vector-attributed hepatotoxicity blocks clinical application in gene therapy

Z Wang, X Zhang - Cytotherapy, 2021 - Elsevier
… associated with acute hepatotoxicity in immunocompromised … acute hepatotoxicity, have
largely limited clinical application. … relationship between AdVs and hepatotoxicity in terms of …

[PDF][PDF] Clinical biochemistry of hepatotoxicity

A Singh, TK Bhat, OP Sharma - J Clinic Toxicol S, 2011 - academia.edu
… both acute hepatotoxicity and … of acute aflatoxicosis resulting in death in humans [154]. hey
have also reported that bacterial lipopolysaccharide [LPS] enhances the acute hepatotoxicity

Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients

MR McGill, H Jaeschke - Expert opinion on drug metabolism & …, 2014 - Taylor & Francis
… Drug hepatotoxicity is currently the single greatest cause of acute liver failure (ALF) in the …
hepatotoxicity. We will begin with an overview of the basic mechanisms of APAP hepatotoxicity

Three-dimensional liver models: State of the art and their application for hepatotoxicity evaluation

X Zhang, T Jiang, D Chen, Q Wang… - Critical Reviews in …, 2020 - Taylor & Francis
… to the acute DILI and chronic liver diseases when treated by hepatotoxic xenobiotics. The
global market for re-construction of 3D liver models with associated hepatotoxicity testing has a …

[PDF][PDF] Hepatotoxicity: treatment, causes and applications of medicinal plants as therapeutic agents

M Thompson, Y Jaiswal, I Wang… - The Journal of …, 2017 - phytopharmajournal.com
… Drug-induced liver injury occurs in many patients with acute liver injury, and … the hepatotoxicity
of the causative agent is helpful in diagnosis. However, documentation of hepatotoxicity in …

Acute hepatotoxicity associated with therapeutic doses of intravenous acetaminophen

SA Seifert, D Kovnat, VE Anderson, JL Green… - Clinical …, 2016 - Taylor & Francis
… acetaminophen-induced hepatotoxicity. We report a case of hepatotoxicity associated with
… Case discussion: We have identified a case of acute liver injury associated with therapeutic …

Human drug hepatotoxicity: a contemporary clinical perspective

DN Assis, VJ Navarro - Expert Opinion on Drug Metabolism & …, 2009 - Taylor & Francis
… on several important clinical aspects of drug hepatotoxicity including clinical diagnosis, …
transaminases to acute liver failure and chronic liver dysfunction. Hepatotoxicity from drugs may …

Hepatotoxicity of antibacterials: pathomechanisms and clinical data

JM Leitner, W Graninger, F Thalhammer - Infection, 2010 - Springer
… induced hepatotoxicity is a frequent cause of liver disease and acuteclinical data based
on epidemiology studies. Certain antibacterial drugs are more frequently linked to hepatotoxicity

Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential

JJ Xu, D Diaz, PJ O'Brien - Chemico-biological interactions, 2004 - Elsevier
… , cutaneous reactions, and hepatotoxicity had the poorest … of acute liver failure [4]. However,
in only approximately half of new pharmaceuticals that produced hepatotoxicity in clinical