Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view

F Guzzi, L Cirillo, RM Roperto, P Romagnani… - … journal of molecular …, 2019 - mdpi.com
… between acute kidney injury (AKI) and chronic kidney disease (… molecular mechanisms,
behind the ability of a single, acute, apparently self-limiting event to drive chronic kidney disease

Molecular mechanisms of kidney injury and repair

S Rayego-Mateos, L Marquez-Expósito… - … journal of molecular …, 2022 - mdpi.com
… participate in the progression of kidney damage (Figure 1) [2,3]. However, CKD is … , death
and acute kidney injury (AKI), which is independent from the cause of CKD. AKI may also have …

Cellular and molecular mechanisms of AKI

…, Acute Dialysis Quality Initiative XIII Working … - Journal of the …, 2016 - journals.lww.com
… Identification of the molecular mechanisms involved in ER stress, such as the PERK-ATF4-…
, including Atg5 and Atg7, blocks autophagy induction in AKI and enhances kidney injury. …

Ferroptosis and acute kidney injury (AKI): molecular mechanisms and therapeutic potentials

Q Feng, X Yu, Y Qiao, S Pan, R Wang… - Frontiers in …, 2022 - frontiersin.org
Acute kidney injury (AKI), which is characterized by a rapid decline in renal function, is …
In this part, we will briefly describe the major regulators and related molecular mechanisms

The role of Nrf2 in acute kidney injury: Novel molecular mechanisms and therapeutic approaches

W Wei, N Ma, X Fan, Q Yu, X Ci - Free Radical Biology and Medicine, 2020 - Elsevier
… of AKI. In this review, we summarized the molecular mechanisms of Nrf2 and ROS in AKI
and … the latest findings on the therapeutic potential of Nrf2 activators in various types of AKI. …

Molecular mechanisms and novel therapeutic approaches to rhabdomyolysis-induced acute kidney injury

N Panizo, A Rubio-Navarro… - Kidney and Blood …, 2015 - karger.com
… to acute kidney injury (AKI) via different mechanisms, such as intratubular obstruction
secondary to protein precipitation, renal vasoconstriction, inflammation, and tubular damage

Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy

ED Morrell, JA Kellum, NM Pastor-Soler, KR Hallows - Critical care, 2014 - Springer
… The most common cause of acute kidney injury (AKI) in hospitalized patients is sepsis.
However, the molecular pathways and mechanisms that mediate septic AKI are not well defined. …

[HTML][HTML] Molecular mechanisms of trauma-induced acute kidney injury: Inflammatory and metabolic insights from animal models

DM Burmeister, BI Gomez, MA Dubick - … (BBA)-Molecular Basis of Disease, 2017 - Elsevier
… with a focus on animal models of AKI due to burn or HS, and … in PubMed using “acute kidney
injury” and “hemorrhage” with … a model of kidney damage by clamping the renal artery to …

Recent advances in molecular mechanisms of acute kidney injury in patients with diabetes mellitus

B Infante, F Conserva, P Pontrelli, S Leo… - Frontiers in …, 2023 - frontiersin.org
… risk factor for AKI. In the next chapter we will analyze the molecular mechanisms through
which … promote cellular dysfunction exposing the kidney to become more vulnerable to AKI. …

Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms

E Ahmadian, SM Hosseiniyan Khatibi… - Reviews in medical …, 2021 - Wiley Online Library
… involvement mainly manifests itself as proteinuria and acute kidney injury (AKI). The
SARS-CoV-2-induced kidney damage is expected to be multifactorial; directly it can infect the kidney