… injury that can persist and predispose to chronic progression of fibrosis. Each epigenetic
modification … ; timely and target-specific epigenetic interventions to the various temporal stages …

… Chromatin Changes in Aki We present a review of epigenetic changes in AKI in the
following order: chromatin organization, DNA methylation, histone modifications, and variants. …

… epigenetics and the mechanisms of epigenetic changes in AKI-to-CKD transition, then focuses
on the role of epigenetic modifications in … reviews the value of epigenetic markers in the …

… risk for the development of chronic kidney disease (CKD). The specific … renal disease (ESRD)
remain unknown, although there is new evidence supporting a role of epigenetic changes. …

… genes in acute kidney injury (AKI) and chronic kidney disease (… modifications and the lack
of coherent epigenetic changes may simply reflect our focus on a small group of modifications. …

… This study represents an in-depth exploration of the epigenetic alterations at several key
AKI… of kidney injury, I/R and LPS, have strikingly different effects on expression and epigenetic …

… Acute kidney injury (AKI) and subsequent kidney repair … epigenetic mechanisms that have
been linked to AKI, describe available evidence linking epigenetic changes to kidney injury …

… Most of our knowledge on the epigenetic changes during AKI is limited due to lack of concrete
… epigenetic modifications are reversible and therefore, therapy to modulate the epigenetic …

… of how the renal cell epigenome is altered by metabolic and … into the pathogenesis of acute
kidney injury (AKI) and CKDs … epigenetic modifications such as histone modifications and …

… Since kidney repair after injury may recapitulate normal morphogenesis, we hypothesized …
epigenetic changes in the renal kallikrein-1 (KLK1) promoter. We considered that changes in …