… renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease
… It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the …

… fibrosis in a swine model of renal ischemia/reperfusion injury [… pro-fibrotic phenotype (EndMT)
leading to renal fibrosis [15]. … in the kidney, promoting the fibrotic changes in CKD …

… of acute kidney disease (AKI) and the consequent development of chronic kidney disease
(CKD) (… The tubules of the kidney play an integral role in the fibrotic response, which ultimately …

… Altogether, a deeper understanding of the cellular and molecular pathways involving fibrosis
in different types of acute kidney injury will be of great importance for the development of …

… (IR) injury with recombinant human erythropoietin (rhEPO) reduces acute kidney injury and
… progression to chronic kidney disease associated with acute injury was also reduced by …

… suppression of the AKI-toCKD transition and fibrotic changes in a rat I/R injury model, although
VEGF-121 did not affect acute kidney damage. Another angiogenic factor, angiopoietin-1, …

… acute kidney injury and can result in poor long-term graft function. Although most of the
patients with acute kidney injury … with long-term changes following acute ischaemia/reperfusion. …

… and interstitial fibrosis when compared with the contralateral control kidneys. This … acute
kidney injury in cats and demonstrates that ischemic acute kidney injury triggers chronic fibrosis…

… In this study, we demonstrated that pro-fibrotic M2 macrophages become predominant in
kidneys during the recovery phase and that they play a critical role in the development and …

… This introduces a new dimension to our understanding of the development of fibrosis
after injury and provides insight into our recent clinical recognition that AKI is an important …