Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice

JS Danobeitia, M Ziemelis, X Ma, LJ Zitur, T Zens… - PloS one, 2017 - journals.plos.org
… to ischemic injury protects kidneys from inflammatory injury and subsequent progression to
fibrosis. … an effective strategy in the prevention of fibrosis after ischemic acute kidney injury. …

[HTML][HTML] Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism

P Mehrotra, JB Patel, CM Ivancic, JA Collett… - Kidney international, 2015 - Elsevier
… recovery from acute kidney injury (AKI) accelerates the transition to chronic kidney disease
(… activation in postischemic kidneys to worsen renal inflammation and fibrosis. Male Sprague–…

Renal inflammation and innate immune activation underlie the transition from gentamicin-induced acute kidney injury to renal fibrosis

AH Albino, FFF Zambom, O Foresto-Neto… - Frontiers in …, 2021 - frontiersin.org
acute kidney injury (AKI) develop an insidious process of renal interstitial collagen accumulation
that eventuates in renal fibrosis (RF) and chronic kidney disease (… of kidney damage in …

Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis

LJ Stallons, RM Whitaker, RG Schnellmann - Toxicology letters, 2014 - Elsevier
Acute kidney injury (AKI) is a disease with mitochondrial dysfunction and a newly established
risk factor for the development of chronic kidney disease (CKD) and fibrosis… early fibrosis

Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury

NI Skrypnyk, P Voziyan, H Yang… - American Journal …, 2016 - journals.physiology.org
… Dose-dependent effects of PM pretreatment on renal oxidative stress and early injury after
ischemia-reperfusion acute kidney injury (IR-AKI). A: experimental design. Mice were either …

A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways

S Furuya, GA Chappell, Y Iwata, T Uehara… - Toxicology and applied …, 2016 - Elsevier
… a severe form of alcohol-associated disease in subjects with pre-existing liver pathologies
such as fibrosis, we aimed to replicate the acute… pro-fibrotic conditions in both liver and kidney. …

Mechanisms of fasting-mediated protection against renal injury and fibrosis development after ischemic acute kidney injury

P Rojas-Morales, E Tapia, JC León-Contreras… - Biomolecules, 2019 - mdpi.com
… Ischemia-reperfusion injury of the kidney may lead to renal fibrosis … rat kidney against
oxidative stress and mitochondrial dysfunction in early acute kidney injury, and also against fibrosis

Heat acclimation ameliorated heat stress-induced acute kidney injury and prevented changes in kidney macrophages and fibrosis

H Goto, M Nakashima, H Nakashima… - American Journal …, 2022 - journals.physiology.org
… stress could induce acute kidney injury. Although … kidney damage remains unclear. This
study showed that 5-day HA ameliorates mouse kidney tubular damage and subsequent fibrosis

Assessment of acute kidney injury and renal fibrosis after renal ischemia protocols in cats

VM Dickerson, DR Rissi, CA Brown… - Comparative …, 2017 - ingentaconnect.com
… a feline model of acute or chronic kidney disease, this study … models of acute kidney injury
and chronic interstitial fibrosis in … used to quantify renal interstitial fibrosis and collagen at 120 …

Acute kidney injury: tubular markers and risk for chronic kidney disease and end-stage kidney failure

HL Tan, JQ Yap, Q Qian - Blood purification, 2016 - karger.com
… , alterations of tubular cell phenotype with cells predominantly in the G2/M phase, interstitial
fibrosis and microvascular rarification related to loss of endothelial–pericyte interactions and …