… The goal of this review is to provide the reader with an overview of human iron homeostasis
and its disorders, emphasizing the exciting new developments in this field during the last 15 …

… [16] suggested that FTH expression in renal proximal tubules was indispensable for
establishing tolerance against Plasmodium spp.-induced acute kidney injury and relied on the …

… the severity of both ischemia-reperfusion– and hemoglobin-mediated kidney injury in mice.
… In conclusion, we found that dysregulated iron homeostasis is a prognostically important …

… active iron, heme iron also can exert toxic effects on the kidney and has been known to induce
acute kidney injury … To confirm that cisplatin was effective in promoting kidney damage, we …

… chronic kidney disease (CKD) and results from the dysregulation of iron metabolism and
erythropoiesis. Hepcidin is a key regulator of iron availability and leads to iron sequestration …

… decreased serum iron, … for severe inflammation-related anemia and iron metabolism
disorders in sepsis patients remains unclear. Moreover, conventional blood transfusion and iron …

… to kidney injury. These data highlight the importance of iron homeostasis in human
ischemia–reperfusion injury … Intraoperative detection of incipient acute kidney injury may be …

… that maintain iron metabolism [3]. This review will focus on the regulation of systemic iron
homeostasis by the hepcidin/ferroportin regulatory circuitry and its impairment in disease. …

… Acute kidney injury (AKI) is one of the most common and severe clinical renal syndromes
with high morbidity and mortality. Ferroptosis is a form of programmed cell death (PCD), is …

… We next investigated the protein levels of key regulators of cellular iron homeostasis. …
acute kidney injury in mice, nuciferine restored intracellular iron homeostasis in HK-2 cells. …