… iron chelation or genetic inhibition of cellular iron uptake. Therefore, iron homeostasis must
be tightly regulated to avoid iron … of the origin and chemistry of iron that makes it suitable for a …

… of kidney injury. Regular variations in iron metabolism indexes in the blood and kidneys
were … Ischemia/reperfusion injury (IRI) is a common pathogenesis of acute kidney injury (AKI) …

… Acute kidney injury (AKI) is a common and critical illness, resulting in severe morbidity and
a high mortality. There is a considerable interest in identifying novel molecular targets for …

… Mitochondria are the core of redox homeostasis and participate in regulating iron homeostasis
and cell metabolism during ferroptosis (Wang et al., 2020). Mitochondrial dysfunction and …

… and the inhibition of ferroptosis to alleviate ischemic acute kidney injury [57]. Pretreatment
with hepcidin prevents renal IRI-induced dysregulation of systemic iron homeostasis and …

… Recently, the role of the kidney in iron handling and metabolism has gained significant
attention.134, 135 Based on experimental studies and studies in humans, iron is increasingly …

… The degradation of heme by HO releases iron in the heme protein-exposed kidney, and …
iron homeostasis by promoting iron storage and the extracellular export of iron, respectively. …

… VDAC regulates mitochondria iron homeostasis through CISD1 which may affect the iron-dependent
cell death of ferroptosis. Translocator protein interacts with VDAC in PINK-PRKN-…

… ferritinophagy might enhance iron accumulation during ferroptotic damage [Citation24]. …
could maintain intracellular iron homeostasis by facilitating ferritin iron storage or release […

… clear about the effect of the liver on iron metabolism and regulation, but we are still constantly
discovering new methods to affect iron metabolism directly or indirectly. As the secretory …