Basics and principles of cellular and systemic iron homeostasis
A Katsarou, K Pantopoulos - Molecular aspects of medicine, 2020 - Elsevier
… iron metabolism is post-transcriptionally controlled by iron regulatory proteins, IRP1 and IRP2,
while systemic iron balance is regulated by the iron … of mammalian iron homeostasis at the …
while systemic iron balance is regulated by the iron … of mammalian iron homeostasis at the …
[HTML][HTML] Farnesoid X receptor protects against cisplatin-induced acute kidney injury by regulating the transcription of ferroptosis-related genes
… of HMOX1 alters iron homeostasis and induces ferroptosis in various cell types [37,38]. High
expression of HMOX1 due to FXR deficiency may fail to regulate iron homeostasis, leading …
expression of HMOX1 due to FXR deficiency may fail to regulate iron homeostasis, leading …
Role of aberrant iron homeostasis in the upregulation of transforming growth factor-β1 in the kidney of angiotensin II-induced hypertensive rats
K Saito, N Ishizaka, T Aizawa, M Sata, N ISO-O… - Hypertension …, 2004 - jstage.jst.go.jp
… and renal failure human kidney disease and various experimental models thereof (1). It
has been shown that blockade of the angiotensin type 1 (AT1) receptor signaling pathway de- …
has been shown that blockade of the angiotensin type 1 (AT1) receptor signaling pathway de- …
Pathophysiology of iron homeostasis during inflammatory states
BJ Cherayil - The Journal of pediatrics, 2015 - jpeds.com
… We will start by summarizing the mechanisms that regulate systemic iron metabolism under
normal conditions, and then describe how inflammation causes abnormalities in this process…
normal conditions, and then describe how inflammation causes abnormalities in this process…
Mechanisms of haemolysis-induced kidney injury
K Van Avondt, E Nur, S Zeerleder - Nature Reviews Nephrology, 2019 - nature.com
… injury, particularly in the kidney 29 . The Fenton reaction was demonstrated to have an important
pathophysiological role in a model of acute kidney injury (… for cellular homeostasis, such …
pathophysiological role in a model of acute kidney injury (… for cellular homeostasis, such …
Misdistribution of iron and oxidative stress in chronic kidney disease
T Nakanishi, T Kuragano, M Nanami… - Free Radical Biology …, 2019 - Elsevier
… We suspected that dysregulation of iron metabolism should … We previously demonstrated
that iron metabolism is … This review provides information regarding iron metabolism …
that iron metabolism is … This review provides information regarding iron metabolism …
Ironing out mechanisms of iron homeostasis and disorders of iron deficiency
… iron and need rapid iron replenishment. Here, we will review cellular and systemic iron
homeostasis and will discuss complications of iron … finding among chronic kidney disease (CKD) …
homeostasis and will discuss complications of iron … finding among chronic kidney disease (CKD) …
Novel faces of fibroblast growth factor 23 (FGF23): iron deficiency, inflammation, insulin resistance, left ventricular hypertrophy, proteinuria and acute kidney injury
… In summary, the role of FGF23 in erythropoiesis and iron metabolism appears relevant, but …
and iron metabolism considering its role at the cross-roads of inflammation and iron utilization…
and iron metabolism considering its role at the cross-roads of inflammation and iron utilization…
Iron Metabolism and Inflammatory Mediators in Patients with Renal Dysfunction
T Matsuoka, M Abe, H Kobayashi - International Journal of Molecular …, 2024 - mdpi.com
… Chronic kidney disease (CKD) affects around 850 million people … kidney disease, and
cardiovascular diseases. This review focuses on the intricate interplay between iron metabolism, …
cardiovascular diseases. This review focuses on the intricate interplay between iron metabolism, …
[HTML][HTML] Hepcidin and iron homeostasis
T Ganz, E Nemeth - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2012 - Elsevier
… with inflammation, chronic kidney disease and some cancers. Hepcidin deficiency causes
… for studying iron metabolism. In laboratory mice, for example, dietary iron absorption and …
… for studying iron metabolism. In laboratory mice, for example, dietary iron absorption and …