Systemic iron homeostasis and erythropoiesis
G Papanikolaou, K Pantopoulos - IUBMB life, 2017 - Wiley Online Library
… utilization, to control immune responses, and to prevent iron toxicity. This review focuses on
systemic iron homeostasis in the context of erythropoiesis, a highly iron-demanding process. …
systemic iron homeostasis in the context of erythropoiesis, a highly iron-demanding process. …
Iron homeostasis and perioperative management of iron deficiency
SR Cleland, W Thomas - BJA education, 2019 - bjaed.org
… This review gives an overview of the physiology of iron metabolism and its impact on key …
An example would be chronic kidney disease (CKD), in which there are apparently normal …
An example would be chronic kidney disease (CKD), in which there are apparently normal …
Erythroferrone structure, function, and physiology: Iron homeostasis and beyond
… iron homeostasis was a novel finding. ERFE met the criteria for the putative erythroid regulator
of iron homeostasis that could explain the observed iron… with chronic kidney disease have …
of iron homeostasis that could explain the observed iron… with chronic kidney disease have …
[HTML][HTML] Role of Nrf2 in protection against acute kidney injury
LM Shelton, BK Park, IM Copple - Kidney International, 2013 - Elsevier
… Acute kidney injury, induced by drugs and other stimuli, is a … molecular mechanisms that
underlie acute kidney injury, and the … Iron metabolism Ferritin (Ft) Facilitates storage of iron in a …
underlie acute kidney injury, and the … Iron metabolism Ferritin (Ft) Facilitates storage of iron in a …
An overview of pathways of regulated necrosis in acute kidney injury
… been published under the term “ferroptosis,” but iron homeostasis and lipid peroxidation
appear to be of high importance in kidney pathologies. In a nicely conducted study, Friedmann …
appear to be of high importance in kidney pathologies. In a nicely conducted study, Friedmann …
Investigations into ferroptosis in methylmercury‐induced acute kidney injury in mice
Y Ye, Y Chen, H Wu, Y Fu, Y Sun… - Environmental …, 2023 - Wiley Online Library
… of cell death accompanied by iron-dependent lipid peroxidation. Previous research has
shown that cadmium exposure triggers ferroptosis by interrupting iron homeostasis and redox …
shown that cadmium exposure triggers ferroptosis by interrupting iron homeostasis and redox …
Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response
JW Deuel, CA Schaer, FS Boretti, L Opitz… - … death & disease, 2016 - nature.com
Intravascular hemolysis can result in hemoglobinuria with acute kidney injury. In this study
we systematically explored two in vivo animal models and a related cell culture system to …
we systematically explored two in vivo animal models and a related cell culture system to …
Hepcidin-ferroportin interaction controls systemic iron homeostasis
… Interestingly, in normal pregnancy, fetal hepcidin concentrations are very low in mice [50]
and do not appear to contribute to baseline iron homeostasis or affect iron transport through …
and do not appear to contribute to baseline iron homeostasis or affect iron transport through …
Iron transport and the kidney
CP Smith, F Thévenod - Biochimica et Biophysica Acta (BBA)-General …, 2009 - Elsevier
… iron homeostasis. Much research has focused on the tissues classically associated with …
accumulation in PT lysosomes and this is associated with kidney injury. In fact, in the study …
accumulation in PT lysosomes and this is associated with kidney injury. In fact, in the study …
Tubular damage biomarkers linked to inflammation or iron metabolism predict acute kidney injury
Methods One hundred adult patients undergoing cardiac surgery in the control arm of a
RCT (NCT00672334) were analyzed. We quantified the following biomarkers in urine: NGAL, …
RCT (NCT00672334) were analyzed. We quantified the following biomarkers in urine: NGAL, …