Polydatin attenuates cisplatin‐induced acute kidney injury by inhibiting ferroptosis
L Zhou, P Yu, T Wang, Y Du, Y Chen… - Oxidative medicine …, 2022 - Wiley Online Library
… In previous studies, polyphenols were often found to be potent iron chelators, and several
polyphenol compounds have been reported to chelate iron and regulate iron homeostasis, …
polyphenol compounds have been reported to chelate iron and regulate iron homeostasis, …
The liver in regulation of iron homeostasis
G Rishi, VN Subramaniam - American Journal of …, 2017 - journals.physiology.org
… proteins and their known roles in the regulation of body iron metabolism. … iron homeostasis
has increased with the progressive identification and analysis of the genes mutated in the iron …
has increased with the progressive identification and analysis of the genes mutated in the iron …
Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells
J Guo, R Wang, F Min - Journal of Leukocyte Biology, 2022 - academic.oup.com
… These results indicated that iron homeostasis in the kidney of rats was disrupted after CLP,
leading to iron accumulation, while ginsenoside Rg1 treatment could restore iron metabolism …
leading to iron accumulation, while ginsenoside Rg1 treatment could restore iron metabolism …
Cell-Specific Iron Metabolism in Kidney Fibrosis: FR-PO1072
CA Campbell, E Patino, K Baqai, D Bhatia… - Journal of the …, 2023 - journals.lww.com
… Background: In the kidney, tubulointerstitial fibrosis can result from incomplete recovery
from acute kidney injury (AKI). Activation of the epidermal growth factor receptor (EGFR) has …
from acute kidney injury (AKI). Activation of the epidermal growth factor receptor (EGFR) has …
Renal cortical hemopexin accumulation in response to acute kidney injury
RA Zager, ACM Johnson… - American Journal of …, 2012 - journals.physiology.org
Hemopexin (Hpx) is a liver-generated acute phase reactant that binds … acute kidney injury
(AKI) triggers renal Hpx accumulation, potentially impacting heme Fe-mediated tubular injury. …
(AKI) triggers renal Hpx accumulation, potentially impacting heme Fe-mediated tubular injury. …
Acute kidney injury: emerging pharmacotherapies in current clinical trials
SW Benoit, P Devarajan - Pediatric Nephrology, 2018 - Springer
… of acute kidney injury (AKI) and targets of emerging pharmacotherapies: Energetic failure …
is an essential element, critical to oxygen transport, cellular energy metabolism, and a wide …
is an essential element, critical to oxygen transport, cellular energy metabolism, and a wide …
Regulation of iron homeostasis: Lessons from mouse models
… cellular iron handling advanced our knowledge how systemic and cellular iron homeostasis
is … insight into mechanisms of iron regulation and/or rare or frequent iron-related disorders. …
is … insight into mechanisms of iron regulation and/or rare or frequent iron-related disorders. …
The physiological functions of iron regulatory proteins in iron homeostasis-an update
DL Zhang, MC Ghosh, TA Rouault - Frontiers in pharmacology, 2014 - frontiersin.org
… iron homeostasis and regulation of erythropoiesis. This review will begin with an overview of
mammalian iron homeostasis, … of IRP1 and IRP2 in cellular and systemic iron homeostasis. …
mammalian iron homeostasis, … of IRP1 and IRP2 in cellular and systemic iron homeostasis. …
Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin
SH Avila-Rojas, OE Aparicio-Trejo… - Food and Chemical …, 2020 - Elsevier
… Curcumin has protective effects in several acute kidney injury models, including that
induced by potassium dichromate (K 2 Cr 2 O 7 ). The protective effect of curcumin in this …
induced by potassium dichromate (K 2 Cr 2 O 7 ). The protective effect of curcumin in this …
Modulation of iron homeostasis with hepcidin ameliorates spontaneous murine lupus nephritis
Y Scindia, E Wlazlo, E Ghias, S Cechova, V Loi… - Kidney international, 2020 - Elsevier
… Hepcidin is known to protect against ischemic acute kidney injury. The direct effect of … cellular
iron metabolism and transport may represent an underinvestigated driver of kidney disease …
iron metabolism and transport may represent an underinvestigated driver of kidney disease …