Role of mitochondrial therapy for ischemic-reperfusion injury and acute kidney injury

N Pabla, A Bajwa - Nephron, 2022 - karger.com
… quickly, resulting in shorter fragmented mitochondria than in sham-operated … mitochondria,
we generated PT-specific mitochondria reporter mice to use as a tool to assess mitochondria

Mitochondria: a therapeutic target in acute kidney injury

Y Ishimoto, R Inagi - Nephrology Dialysis Transplantation, 2016 - academic.oup.com
… Investigations of mitochondria in nephrology lag behind those in other fields like cardiology,
mitochondria are already in use in other fields. The potential for mitochondria-based therapy

The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential

X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… and the specific pathogenic mechanisms of mitochondrial dysfunction in the progression of
… of mitochondrial-targeted therapeutic agents for the treatment of mitochondrial dysfunction-…

Mitochondria-targeted therapies for acute kidney injury

LC Tábara, J Poveda, C Martin-Cleary… - Expert reviews in …, 2014 - cambridge.org
… of mitochondrial genes and proteins. Finally, we summarise the current status of novel
therapeutic strategies specifically targeting mitochondria such as mitochondrial permeability …

Mitochondria in acute kidney injury

KM Ralto, SM Parikh - Seminars in nephrology, 2016 - Elsevier
Acute kidney injury (AKI) continues to be a significant contributor to morbidity, mortality, and
mitochondria in AKI, while also proposing potential therapeutic targets and future therapies. …

Mesenchymal stem cell therapy targeting mitochondrial dysfunction in acute kidney injury

L Zhao, C Hu, P Zhang, H Jiang, J Chen - Journal of Translational …, 2019 - Springer
… Defects in mitochondrial function are key pathophysiological changes during acute kidney
injury (AKI… Below, we will discuss the mechanism by which MSC therapy targets mitochondrial

[HTML][HTML] Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment

Q Huang, Y Yang, T Zhao, Q Chen, M Liu, S Ji, Y Zhu… - Bioactive materials, 2023 - Elsevier
… in protecting mitochondria by reducing mitochondrial ROS and … mitochondria for AKI,
and give inspiration for the treatment of many major diseases closely related to mitochondria

Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury

Y Chen, Z Li, H Zhang, H Chen, J Hao, H Liu… - Cell Death Discovery, 2024 - nature.com
… efficacy and safety of mitochondria-targeted therapy approaches, we hope that mitochondrial
therapeutic targets become a strategy to improve kidney injury and disease in the future. …

[HTML][HTML] Mitochondrial dysfunction in kidney injury, inflammation, and disease: Potential therapeutic approaches

D Bhatia, A Capili, ME Choi - Kidney research and clinical practice, 2020 - ncbi.nlm.nih.gov
… DNA derived from damaged cells also act as damage-… kidney injury. This review provides
a comprehensive overview of the role of mitochondrial dysfunction in acute kidney injury and …

Intervention of mitochondrial activity attenuates cisplatin-induced acute kidney injury

Y Yang, Y Fu, P Wang, S Liu, Y Sha, Y Zhang… - … urology and nephrology, 2019 - Springer
kidney injury, we used rotenone, a specific mitochondrial … -term treatment was usually
used to induce mitochondrial … In this study, we supposed rotenone treatment at a lower dose …