Ferroptosis and acute kidney injury (AKI): molecular mechanisms and therapeutic potentials

Q Feng, X Yu, Y Qiao, S Pan, R Wang… - Frontiers in …, 2022 - frontiersin.org
… cure the disease. Relevant studies have also shown that the occurrence of AKI increases …
potential risk of patients developing chronic kidney disease (CKD) and end-stage renal disease

Salt inducible kinase signaling networks: implications for acute kidney injury and therapeutic potential

M Taub - International Journal of Molecular Sciences, 2019 - mdpi.com
… A number of signal transduction pathways are activated during Acute Kidney Injury (AKI).
Of particular … This report is concerned with the involvement of SIK in Acute Kidney Injury (AKI). …

[HTML][HTML] Autophagy and necroptosis in cisplatin-induced acute kidney injury: Recent advances regarding their role and therapeutic potential

N Alassaf, H Attia - Frontiers in Pharmacology, 2023 - frontiersin.org
… witnessed a burgeoning interest owing to their potential to regulate and alleviate CP-… potential
roles of both autophagy and necroptosis in CP-induced AKI. We also explore the potential

P53 in kidney injury and repair: mechanism and therapeutic potentials

C Tang, Z Ma, J Zhu, Z Liu, Y Liu, Y Liu, J Cai… - … & therapeutics, 2019 - Elsevier
Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. Besides its
acute … to the occurrence and progression of chronic kidney diseases (CKD). Accumulating …

[HTML][HTML] Tetramethylpyrazine: An active ingredient of Chinese herbal medicine with therapeutic potential in acute kidney injury and renal fibrosis

J Li, X Gong - Frontiers in Pharmacology, 2022 - frontiersin.org
kidney disease (CKD) are very tightly linked by each other, and AKI is also an important
inducement of CKD, we thus summarized the potential of … , TMP has the therapeutic potential of …

[HTML][HTML] Stem cell-derived extracellular vesicles as potential therapeutic approach for acute kidney injury

M Quaglia, G Merlotti, A Colombatto, S Bruno… - Frontiers in …, 2022 - frontiersin.org
… the potential impact of extracellular vesicles on the mechanisms of transition from acute kidney
injury to chronic kidney disease… Their therapeutic potential is revolutionizing regenerative …

Potential targeted therapy and diagnosis based on novel insight into growth factors, receptors, and downstream effectors in acute kidney injury and acute kidney injury …

LI Gao, X Zhong, J Jin, J Li, X Meng - … transduction and targeted therapy, 2020 - nature.com
… In addition, growth factor-modified MSCs show superior therapeutic potential compared
to that of unmodified controls. In this review, we summarized the current therapeutic and …

Short-term preconditioning enhances the therapeutic potential of adipose-derived stromal/stem cell-conditioned medium in cisplatin-induced acute kidney injury

JM Overath, S Gauer, N Obermüller, R Schubert… - Experimental cell …, 2016 - Elsevier
The development of new strategies to preserve renal function after acute kidney injury (AKI)
is necessary due to limited clinical intervention options. The organ-protective effects of …

[HTML][HTML] Potential therapeutic applications of circular RNA in acute kidney injury

Z Li, J Xing - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Acute kidney injury (AKI) is a common clinical syndrome … to chronic kidney disease or
end-stage renal disease. Treatment … in disease occurrence and development, and has potential

Factors affecting the transition of acute kidney injury to chronic kidney disease: Potential mechanisms and future perspectives

J Ogbadu, G Singh, D Aggarwal - European Journal of Pharmacology, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a rapid loss of kidney … , AKI may progress to chronic
kidney disease (CKD) even after … both injury and repair, epigenetic changes underlying kidney