[HTML][HTML] Pathophysiology of acute kidney injury

DP Basile, MD Anderson, TA Sutton - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
… to vasodilator therapy. It is suggested that targeting the extension phase represents an area
potential of treatment with the greatest possible impact. The underlying basis of renal injury

Biomarkers of acute kidney injury

VS Vaidya, MA Ferguson… - Annu. Rev. Pharmacol …, 2008 - annualreviews.org
… a) Kidney injury continuum: The process of acute kidney injury … from increased risk to
damage followed by decrease in … a potential biomarker for monitoring progression of chronic …

Src family kinases: a potential therapeutic target for acute kidney injury

N Li, G Lin, H Zhang, J Sun, M Gui, Y Liu, W Li, J Liu… - Biomolecules, 2022 - mdpi.com
… on its role in the kidney. Acute kidney injury (AKI) is a disease with complex pathogenesis, …
the progression of AKI to developing chronic kidney disease (CKD). The mortality rate of this …

Exercise as a therapeutic option for acute kidney injury: mechanisms and considerations for the design of future clinical studies

A Asad, JO Burton, DS March - BMC nephrology, 2020 - Springer
Acute kidney injury (AKI) is a known risk factor for chronic kidney disease (CKD) and end
stage kidney disease (… This study therefore demonstrates a potential anti-fibrotic mechanism by …

Mesenchymal stem cells as therapeutic agents and novel carriers for the delivery of candidate genes in acute kidney injury

Y Liu, J Fang - Stem Cells International, 2020 - Wiley Online Library
… modification strategies targeted at optimizing the therapeutic potential of MSCs in AKI. … AKI
in the context of MSC therapy. The therapeutic potential of MSCs was decreased considerably …

Extracellular vesicles derived from mesenchymal stem cells as a potential therapeutic agent in acute kidney injury (AKI) in felines: review and perspectives

MM Kraińska, N Pietrzkowska, E Turlej… - … cell research & therapy, 2021 - Springer
disease, eg, EVs isolated from urine can reflect the development of AKI [17]. However, their
therapeutic potential … In major perspectives, the promising aspects of using EVs in therapeutic

Mesenchymal stromal cell uses for acute kidney injury—Current available data and future perspectives: A mini-review

S Zilberman-Itskovich, S Efrati - Frontiers in Immunology, 2020 - frontiersin.org
… MSCs have the potential to ameliorate the secondary damage, and recent studies have shed
… MSCs therapy, the newly discovered mechanisms of action, and their potential application …

Kidney-targeted redox scavenger therapy prevents cisplatin-induced acute kidney injury

RM Williams, J Shah, E Mercer, HS Tian… - Frontiers in …, 2022 - frontiersin.org
… We found that edaravone-loaded MNPs exhibited substantial therapeutic potential in a murine
… on acute kidney injury, we anticipate future work will evaluate this potential therapeutic

[HTML][HTML] New trends in pharmacological treatment of acute kidney injury

HMI Abdallah - Asian Pacific Journal of Tropical Biomedicine, 2021 - journals.lww.com
… However, the extensive clinical trials on the therapeutic potential of EVs in the treatment AKI
… isolated phytochemicals with potential therapeutic effects on kidney injury will be reviewed …

Acute kidney injury

R Bellomo, JA Kellum, C Ronco - The Lancet, 2012 - thelancet.com
injury or expedite recovery; thus, treatment is supportive. … renal replacement therapy if acute
kidney injury is severe and … do not have premorbid chronic kidney disease, they typically …