Sepsis-associated acute kidney injury—treatment standard

A Zarbock, JL Koyner, H Gomez… - Nephrology Dialysis …, 2024 - academic.oup.com
Sepsis is a host's deleterious response to infection, which could lead to life-threatening
organ dysfunction. Sepsis-associated acute kidney injury (SA-AKI) is the most frequent organ …

[HTML][HTML] Acute kidney injury and chronic kidney disease: an integrated clinical syndrome

LS Chawla, PL Kimmel - Kidney international, 2012 - Elsevier
… of acute kidney injury (AKI) tend to do well and fully recover renal function appears to be
flawed. AKI can cause end-stage renal disease (… We review the potential mechanistic factors …

Recent updates on mesenchymal stem cell based therapy for acute renal failure

A Missoum - Current urology, 2020 - karger.com
Acute kidney injury, formerly known as acute renal failure, is a pathological condition in …
Another strategy to boost therapeutic potential of AD-MSCs is to pretreat it with other biochemical …

[HTML][HTML] Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
potential risks of chronic kidney disease (CKD), cardiovascular disease, and end-stage renal
disease (… And strategies targeting ferroptosis showed great therapeutic potential. Our study …

Research progress on regulatory T cells in acute kidney injury

Y Wang, Y Tao - Journal of immunology research, 2015 - Wiley Online Library
… the role of Tregs and their therapeutic potential in AKI. … the kidney function declined, and
kidney damage was markedly exacerbated, which suggested that Tregs alleviate kidney damage

[HTML][HTML] The biomarkers for acute kidney injury: A clear road ahead?

ZY Peng - Journal of Translational Internal Medicine, 2016 - degruyter.com
Risk stratification of AKI [3] is important for acute decompensated heart failure (ADHF). For
predicting intrinsic AKI on the first day of intensive care unit (ICU) admission, a combination of …

In vivo models of acute kidney injury

SN Heyman, M Khamaisi, S Rosen… - … Today: Disease Models, 2010 - Elsevier
… evaluation of a therapeutic intervention. Therefore, potential confounding factors should be
controlled for especially in compound experimental settings, such as fluid status, body and …

[HTML][HTML] Limonin, a natural ERK2 agonist, protects against ischemic acute kidney injury

X Zhou, Y Xiang, D Li, M Zhong, X Hong… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
… An abrupt loss of kidney function characterizes acute kidney injury (AKI) occurring in a few
… favorable safety profiles, limonin exhibits therapeutic potential in mitigating ischemic AKI. …

Pathophysiology of cisplatin‐induced acute kidney injury

A Ozkok, CL Edelstein - BioMed research international, 2014 - Wiley Online Library
… A known complication of cisplatin administration is acute kidney injury (AKI). The … Potential
therapies for cisplatin-induced AKI based on pathophysiological mechanisms of injury include …

[HTML][HTML] Thirty-eight-negative kinase 1 Is a mediator of acute kidney injury in experimental and clinical traumatic hemorrhagic shock

R Halbgebauer, E Karasu, CK Braun, A Palmer… - Frontiers in …, 2020 - frontiersin.org
… driver of organ damage. In future studies, we will address the therapeutic potential of direct
TNK1 inhibition in the context of severe tissue trauma with different degrees of additional HS. …