… We conducted a retrospective study to define the significance of Ph in myelodysplastic
syndrome and acute leukemia in the adult patients at this institution and the literature was …

… myelodysplastic syndrome and acute myeloid leukaemia following melphalan and
cyclophosphamide treatment … A report to the Medical Research Council's working party on …

The myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are both
hematopoietic stem cell disorders. However, while leukemic stem cells have been revealed by …

… Acute megakaryoblastic Acute panmyelosis with myelofibrosis Other AML-NOS (rare) Acute
leukemia with multilineage dysplasia de novo or secondary to MDS, MDS/MPD or CMPD …

… disease or evolution to acute leukaemia was 30% for all patients. 18 developed acute
leukaemia 3-22 … Patients with tMDS had significantly higher BM blasts over p-MDS (P = 0.005). …

… Treatment of older adults with acute myeloid leukemia (AML) or myelodysplastic syndromes
(MDS) is challenging because of disease morbidity and associated treatments. Both …

… impression that progression to acute leukemia is the major cause of … Although transformation
to acute leukemia has been reported … with MDS developedtransformation to acute leukemia. …

… , although there are frequent transitional forms, and as the natural history of the MDS unfolds
they … towards acute leukaemia makes necessary to investigate new methods of treatment for …

… of myelodysplastic syndrome (MDS) and adult acute leukemia … Durable remissions of
relapsed leukemia and MDS after … The efficacy of DLI in leukemias and MDS has been limited …

… Transformation to acute leukemia occurs in up to 40% of patients, with the percentage varying
considerably by subtype.[1], [7], [17], [20], [21], [22] Although progression to frank AML is a …