NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia

YW Lin, C Slape, Z Zhang, PD Aplan - Blood, 2005 - ashpublications.org
… to acute leukemia, as well as the relatively long latency prior to leukemic transformation,
suggests that NHD13 requires cooperative genetic events to produce an acute leukemia. On the …

Risk of acute leukemia and myelodysplastic syndromes in patients with monoclonal gammopathy of undetermined significance (MGUS): a population-based study of …

LE Roeker, DR Larson, RA Kyle, S Kumar… - Leukemia, 2013 - nature.com
… an increased risk of acute leukemia and myelodysplastic syndromes (MDS) in persons with
… diagnosis of acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and MDS. A …

Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7

H Hasle, M Arico, G Basso, A Biondi, AC Rajnoldi… - Leukemia, 1999 - nature.com
We reviewed the clinical features, treatment, and outcome of 100 children with myelodysplastic
syndrome (MDS), juvenile myelomonocytic leukemia (JMML), and acute myeloid …

Point mutations of the N‐ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia

V Vasioukhin, P Anker, P Maurice… - British journal of …, 1994 - Wiley Online Library
… mutations of the N-ras gene in the DNA of the plasma, the blood cells and, when available,
the bone marrow of patients with acute myeloid leukaemia or myelodysplastic syndrome. …

Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia

AS Watson, M Mortensen, AK Simon - Cell cycle, 2011 - Taylor & Francis
… stem cells (HSCs) may be implicated in leukemia. Indeed, mice lacking Atg7 in HSCs …
resembling human myelodysplastic syndrome (MDS) progressing to acute myeloid leukemia (AML)…

… features and outcomes of patients with Shwachman-Diamond syndrome and myelodysplastic syndrome or acute myeloid leukaemia: a multicentre, retrospective …

KC Myers, E Furutani, E Weller, B Siegele… - The Lancet …, 2020 - thelancet.com
… patients with acute myeloid leukaemia or myelodysplastic syndrome and Shwachman-Diamond
syndrome results from both high treatment related mortality and high disease resistance. …

Myelodysplastic syndrome

G Mufti, AF List, SD Gore, AYL Ho - ASH Education Program …, 2003 - ashpublications.org
… In a Phase I study of lonafarnib administered in a continuous schedule in patients with
advanced CML, MDS, CMML or acute leukemia, clinical benefit or hematological improvement …

Diagnosis, classification, and cytogenetics of myelodysplastic syndromes

T Vallespí, M Imbert, C Mecucci, C Preudhomme… - …, 1998 - haematologica.org
… Some authors propose considering all patients with more than 20% of blast cells in
peripheral blood or bone marrow as having acute leukemia. Chronic myelomonocytic …

Clinical significance of phenotypic features of blasts in patients with myelodysplastic syndrome

K Ogata, K Nakamura, N Yokose… - Blood, The Journal …, 2002 - ashpublications.org
… ) from blood and marrow samples of 95 patients with various MDS subtypes and 21 patients
with acute leukemia transformed from MDS (AL-MDS). Flow cytometry revealed that a high …

Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation

J Offman, G Opelz, B Doehler, D Cummins, O Halil… - Blood, 2004 - ashpublications.org
Immunosuppression after organ transplantation is an acknowledged risk factor for skin cancer
and lymphoma. We examined whether there was also an excess of leukemia in patients …