… failures, our data suggested that treatment with aptTNF-α/aptTNF-α-PEG not only rescued
acute liver damage … aptTNF-α/aptTNF-α-PEG in ALF. Taken together, we showed that aptTNF-…

… Acute liver failure (ALF) due to ischemic or toxic liver injury is … of hepatocytes and may lead
to hepatic encephalopathy (HE), a … expression of tumor necrosis factor-alpha (TNF-α) in liver, …

… Anti-TNF-α-associated acute liver failure displays somewhat … with anti-TNF-α-induced
drug-induced liver injury. Infliximab was … in acute liver failure, eight of the nine cases of anti-TNF-α-…

… liver injury. The innate immune response is activated much more rapidly compared with
adaptive immunity, particularly in acute liver injury … Acute liver failure (ALF) is a syndrome of …

… the pathogenetic factors that drive acute liver injury. These included consideration of (… liver
injury, (2) the role of cytokine release in perpetuating liver injury and causing multiorgan failure…

… Our results suggested that TNF-α had a dual role in acute liver injury. It was regulated might
via the … Meanwhile, our findings provide a reference for clinical treatment of acute liver injury. …

… inflammation in acute liver failure, its relation to disease progression, exacerbation of liver
injury and development of innate immune dysfunction and extra-hepatic organ failure as …

… , acute decompensation of Wilson’s disease, reactivation of chronic hepatitis B, and autoimmune
hepatis – in fact, chronic liver diseases – are considered as cases of acute liver failure. …

… In conclusion, TNFα hepatotoxicity in Gal/LPS-induced acute liver failure involves Fas/FasL-dependent
cell death in either a fratricidal or suicidal manner. Thus, when developing anti-…

… Tumor necrosis factor-a (TNF-a) and transforming growth factor-fl (TGF-p) have a … in acute
liver injury and repair. Therefore, we investigated these two cytokines in acute liver damage. …