… evaluate a series of novel acylhydrazone derivatives based on these heterocycles. … novel
acylhydrazone derivatives based on pharmacophores hybridization. We utilized acylhydrazone …

… , and evaluated as potential antitumor agents a series of 2-hydroxybenzylidene derivatives
of the N-(… to be non-toxic, making them good candidates for further study as antitumor agents. …

… , and identified novel N-acyl hydrazone derivatives 7a-e, 8a-e… that N-acyl hydrazone derivatives
exhibit significant and … all synthesized N-acyl hydrazone derivatives exhibited very good …

… a novel class of anticancer agents, we report herein the synthesis and antitumor effect of
new compounds, including acylhydrazone moiety as a linker between BT and phenyl scaffolds. …

… A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential
… ) and biological activities as potential anticancer agents on proliferation of A549 and CCD-…

… the anticancer activity of amide derivatives. It is a … derivatives, in particular, acylhydrazone
derivatives, exhibit potent coordination in multiple forms. First of all, acylhydrazone derivatives …

… anticancer agents with multi-targeted molecular mechanisms, we combined the diaryl urea
moiety from sorafenib and N-acylhydrazone… urea derivatives bearing Nacylhydrazone moiety (…

… Particularly, the N-acylhydrazone scaffold served as a … anticancer agents acting via different
mechanisms. An updated summary of the anticancer activity of N-acylhydrazone derivatives …

… 21 (Figure 17) could be used in therapy as an antitumor agent with insignificant effects on
normal cell lines due to the fact that it induces apoptosis by depolarizing the mitochondrial …

… In order to develop novel chemotherapeutic agents with potent anticancer activities, a series
of dehydroabietic acid (DHA) derivatives bearing an acylhydrazone moiety were designed …