Adaptive response of T and B cells in atherosclerosis

DFJ Ketelhuth, GK Hansson - Circulation research, 2016 - Am Heart Assoc
… In this review, we discuss important studies on the function of T- and B-cell immunity in
atherosclerosis and their manipulation to develop novel therapeutic strategies against …

Role of the adaptive immune system in atherosclerosis

K Ley - Biochemical Society Transactions, 2020 - portlandpress.com
… Thus, both T and B cells play critical roles in atherosclerosis. Modifying the adaptive
immune response to ApoB holds promise for preventing atherosclerosis and reducing disease …

[HTML][HTML] Adaptive immune responses in human atherosclerosis

S Lee, B Bartlett, G Dwivedi - International journal of molecular sciences, 2020 - mdpi.com
… a crucial role in the atherosclerotic plaque establishment and … adaptive immune cells in
human atherosclerotic plaques and review the clinical utility of profiling circulating immune cells

Readapting the adaptive immune response–therapeutic strategies for atherosclerosis

AP Sage, Z Mallat - British Journal of Pharmacology, 2017 - Wiley Online Library
… Alternative strategies to neutralize pro-inflammatory adaptive responses include blocking
critical co-stimulatory pathways or other indirect anti-inflammatory treatments such as B …

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
… innate and adaptive immune components that orchestrate inflammation in atherosclerosis, …
immune mediators on non-immune cells in atherosclerotic plaques are outside the scope of …

The influence of innate and adaptive immune responses on atherosclerosis

JL Witztum, AH Lichtman - Annual Review of Pathology …, 2014 - annualreviews.org
… These OSEs and others are present in atherosclerotic lesions and act as major antigens
stimulating innate and adaptive responses that affect the progression of vascular disease. …

[HTML][HTML] Once upon a time: the adaptive immune response in atherosclerosis—a fairy tale no more

M Le Borgne, G Caligiuri, A Nicoletti - Molecular Medicine, 2015 - Springer
response to slow down atherosclerosis? In this retrospective, we review growing knowledge
about the role of T and B cells in atherosclerosis … of the immune response in atherosclerosis, …

An overview of the innate and adaptive immune system in atherosclerosis

M Mohmmad‐Rezaei, R Arefnezhad, R Ahmadi… - Iubmb …, 2021 - Wiley Online Library
… and activation of immune cells. This study aims to describe the function of different cells
of adaptive and innate immune systems in progression and suppression of atherosclerosis. …

Immune-inflammatory responses in atherosclerosis: role of an adaptive immunity mainly driven by T and B cells

DA Chistiakov, AN Orekhov, YV Bobryshev - Immunobiology, 2016 - Elsevier
… The adaptive response plays a prominent role in atherogenesis. Effector T cells produce …
In atherosclerosis, T helper (Th) cells could recognize self-antigens and induce a humoral …

Innate and adaptive immunity in atherosclerosis

K Miteva, R Madonna, R De Caterina… - Vascular …, 2018 - Elsevier
… , activating Th17 cells that amplify immune cell recruitment in atherosclerotic plaques [65].
NETs have been discovered in clinically important thrombi in atherosclerotic plaques [66]. …